Alchornea cordifolia
Species
KNApSAcK Entry
| Organism name | Alchornea cordifolia |
|---|---|
| Genus | Alchornea |
| Family | Euphorbiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Alchornea cordifolia |
|---|---|
| Linked NCBI taxonomy ID | 316697 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Euphorbiaceae |
|---|---|
| ID | 3977 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00034781
|
Acetylaleuritolic acid
/ 3-Acetyl aleuritolic acid / (+)-Aleuritolic acid acetate / (+)-3-Acetyl aleuritolic acid |
CHEMBL439422
|
C014947
|
No. 177 |
|
|||
|
C00019308
|
Doursterol
/ Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside |
CHEMBL197711
CHEMBL506678 CHEMBL2304043 |
C011015
|
5 / 4 / 2 | 0 / 3 | No. 520 |
|
|
|
C00035576
|
di(2-Ethylhexyl) phthalate
|
CHEMBL402794
CHEMBL1242017 |
D004051
|
100 / 41 / 36 | 39 / 35 | No. 6750 |
|
Human Protein / Gene in interactions
111 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003672 C00035576 | 1 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 C00019308 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003672 C00035576 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003672 C00035576 | 1 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 C00035576 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003672 C00035576 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 C00019308 | 4 / 2 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 C00019308 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003672 C00035576 | 0 / 1 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00019308 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00019308 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00035576 | 2 / 1 |
| P29466 | Caspase-1 | C14 | C00035576 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00035576 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00035576 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00035576 | 2 / 2 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00035576 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00035576 | 3 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00035576 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00035576 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00035576 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00035576 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00035576 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00035576 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00035576 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00035576 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00035576 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00035576 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00035576 | 1 / 8 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00035576 | 2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00035576 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00035576 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00035576 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00035576 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00035576 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00035576 | 0 / 0 |
| P07858 | Cathepsin B | C1A | C00035576 | 0 / 1 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00035576 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00035576 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00035576 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00035576 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00035576 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00035576 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00035576 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00035576 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00035576 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00035576 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00035576 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00035576 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00035576 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00035576 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00035576 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00035576 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00035576 | 1 / 0 |
| P08246 | Neutrophil elastase | S1A | C00035576 | 2 / 1 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00035576 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00035576 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00035576 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00035576 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00035576 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00035576 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00035576 | 2 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00035576 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00035576 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00035576 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00035576 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00035576 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00035576 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00035576 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00035576 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00035576 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00035576 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00035576 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00035576 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00035576 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00035576 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00035576 | 0 / 3 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00035576 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00035576 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00035576 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00035576 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00035576 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00035576 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00035576 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00035576 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00035576 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00035576 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00035576 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00035576 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00035576 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00035576 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00035576 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00035576 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00035576 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00035576 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00035576 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00035576 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00035576 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00035576 | 0 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00035576 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 |
39 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00035576
|
| 34 | ACADM, ACAD1, MCAD, MCADH | acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) |
C00035576
|
| 37 | ACADVL, ACAD6, LCACD, VLCAD | acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9) |
C00035576
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00035576
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00035576
|
| 367 | AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | androgen receptor |
C00035576
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00035576
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00035576
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00035576
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00035576
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00035576
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00035576
|
| 1036 | CDO1 | cysteine dioxygenase type 1 (EC:1.13.11.20) |
C00035576
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00035576
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00035576
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00035576
|
| 13117 |
C00035576
|
||
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00035576
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00035576
|
| 3073 | HEXA, TSD | hexosaminidase A (alpha polypeptide) (EC:3.2.1.52) |
C00035576
|
| 3074 | HEXB, ENC-1AS | hexosaminidase B (beta polypeptide) (EC:3.2.1.52) |
C00035576
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00035576
|
| 27074 | LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 | lysosomal-associated membrane protein 3 |
C00035576
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00035576
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00035576
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00035576
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00035576
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00035576
|
| 8648 | NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74 | nuclear receptor coactivator 1 (EC:2.3.1.48) |
C00035576
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00035576
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00035576
|
| 9061 | PAPSS1, ATPSK1, PAPSS, SK1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (EC:2.7.1.25 2.7.7.4) |
C00035576
|
| 9060 | PAPSS2, ATPSK2, BCYM4, SK2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (EC:2.7.1.25 2.7.7.4) |
C00035576
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00035576
|
| 5467 | PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB | peroxisome proliferator-activated receptor delta |
C00035576
|
| 6821 | SUOX | sulfite oxidase (EC:1.8.3.1) |
C00035576
|
| 7077 | TIMP2, CSC-21K, DDC8 | TIMP metallopeptidase inhibitor 2 |
C00035576
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00035576
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00035576
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (57)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (44)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00932 | Tropical calcific pancreatitis |
P07858
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
38 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D002493 | Central Nervous System Diseases |
C00019308
|
| D003072 | Cognition Disorders |
C00019308
|
| D013118 | Spinal Cord Diseases |
C00019308
|
| D000014 | Abnormalities, Drug-Induced |
C00035576
|
| D000022 | Abortion, Spontaneous |
C00035576
|
| D000138 | Acidosis |
C00035576
|
| D000236 | Adenoma |
C00035576
|
| D000858 | Anovulation |
C00035576
|
| D006528 | Carcinoma, Hepatocellular |
C00035576
|
| D003876 | Dermatitis, Atopic |
C00035576
|
| D012734 | Disorders of Sex Development |
C00035576
|
| D005234 | Fatty Liver |
C00035576
|
| D005327 | Fetal Resorption |
C00035576
|
| D005355 | Fibrosis |
C00035576
|
| D005832 | Genital Diseases, Male |
C00035576
|
| D005921 | Glomerulonephritis |
C00035576
|
| D006058 | Gonadal Disorders |
C00035576
|
| D006059 | Gonadal Dysgenesis |
C00035576
|
| D006529 | Hepatomegaly |
C00035576
|
| D006949 | Hyperlipidemias |
C00035576
|
| D006965 | Hyperplasia |
C00035576
|
| D006973 | Hypertension |
C00035576
|
| D007021 | Hypospadias |
C00035576
|
| D007674 | Kidney Diseases |
C00035576
|
| D007681 | Kidney Papillary Necrosis |
C00035576
|
| D008107 | Liver Diseases |
C00035576
|
| D008113 | Liver Neoplasms |
C00035576
|
| D008114 | Liver Neoplasms, Experimental |
C00035576
|
| D009336 | Necrosis |
C00035576
|
| D009765 | Obesity |
C00035576
|
| D010049 | Ovarian Diseases |
C00035576
|
| D011041 | Poisoning |
C00035576
|
| D011297 | Prenatal Exposure Delayed Effects |
C00035576
|
| D011469 | Prostatic Diseases |
C00035576
|
| D013733 | Testicular Diseases |
C00035576
|
| D014564 | Urogenital Abnormalities |
C00035576
|
| D015430 | Weight Gain |
C00035576
|
| D015431 | Weight Loss |
C00035576
|