Millettia conraui
Species
KNApSAcK Entry
| Organism name | Millettia conraui |
|---|---|
| Genus | Millettia |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Millettia |
|---|---|
| Linked NCBI taxonomy ID | 53625 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003738
|
beta-Amyrin
/ beta-Amirin / beta-Amyrine / beta-Amyrenol |
C036380
|
0 / 4 | No. 23 | No. 51 |
|
||
|
C00009913
|
5-Methoxydurmillone
/ 5,6-Dimethoxy-3',4'methylenedioxy-6'',6''-dimethylpyrano[2'',3'':7,8]isoflavone |
No. 24 | No. 15 |
|
||||
|
C00009441
|
Durmillone
|
No. 24 | No. 15 |
|
||||
|
C00019099
|
Conrauinone A
/ 5,6,2'-Trimethoxy-4',5'-methylenedioxy-6'',6''-dimethylpyrano[2'',3'':7,8]isoflavone |
No. 24 | No. 15 |
|
||||
|
C00009406
|
Fujikinetin
/ 7-Hydroxy-6-methoxy-3',4'-methylenedioxyisoflavone |
CHEMBL485985
|
No. 27 | No. 15 |
|
|||
|
C00023770
|
Sitosterol
/ Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00019082
|
Conrauinone C
/ 7-Hydroxy-5-methoxy-4'-geranyloxyisoflavone |
No. 354 |
|
|||||
|
C00019083
|
Conrauinone D
/ 7-Hydroxy-4'-geranyloxyisoflavone |
No. 354 |
|
|||||
|
C00019308
|
Doursterol
/ Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside |
CHEMBL197711
CHEMBL506678 CHEMBL2304043 |
C011015
|
5 / 4 / 2 | 0 / 3 | No. 520 |
|
|
|
C00030805
|
1-Docosanol
/ n-Docosanol |
CHEMBL1200453
|
C529236
|
1 / 0 / 0 | No. 732 |
|
||
|
C00019100
|
Conrauinone B
/ 6-Methyoxy-3',4'-methylendedoxy-7-(7-hydroxy-3,7-dimethyl-2(E),5''-octadienyloxy)isoflavone |
No. 2019 |
|
Human Protein / Gene in interactions
18 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00019308 C00023770 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00019308 C00023770 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00019308 C00023770 | 4 / 2 |
| P06746 | DNA polymerase beta | Enzyme | C00019308 C00023770 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00019308 C00023770 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00023770 | 1 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00023770 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00023770 | 0 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00030805 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00023770 | 3 / 2 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00023770 | 2 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00023770 | 4 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00023770 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00023770 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00023770 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00023770 | 0 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00023770 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00023770 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (19)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
KEGG DISEASE (12)
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
7 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D002493 | Central Nervous System Diseases |
C00019308
|
| D003072 | Cognition Disorders |
C00019308
|
| D013118 | Spinal Cord Diseases |
C00019308
|
| D005157 | Facial Pain |
C00003738
|
| D006930 | Hyperalgesia |
C00003738
|
| D007249 | Inflammation |
C00003738
|
| D010146 | Pain |
C00003738
|