Eugenia sandwicensis

• Index
• Plant Species
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Eugenia sandwicensis
Genus	Eugenia
Family	Myrtaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Eugenia
Linked NCBI taxonomy ID	119950
Linked level	genus

Family

Family in NCBI taxonomy	Myrtaceae
ID	3931

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00030742	Maslinic acid / Crategolic acid / 2alpha,3beta-Dihydroxyolean-12-en-28-oic acid	CHEMBL201515 CHEMBL383749 CHEMBL482673 CHEMBL577380	C412811	8 / 5 / 4		No. 13	No. 51
C00030459	Hederagenin	CHEMBL486400 CHEMBL492472 CHEMBL1436053	C025763	7 / 11 / 11		No. 13	No. 51
C00029724	Arjunolic acid	CHEMBL464466 CHEMBL1774425 CHEMBL1797308	C061640	2 / 0 / 0	0 / 2	No. 13	No. 51
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00007558	Syringaldehyde / 4-Hydroxy-3,5-dimethoxybenzaldehyde	CHEMBL225303	C069665			No. 856

Human Protein / Gene in interactions

42 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00019308 C00030459 C00030742	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003741 C00029724	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003741 C00019308	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003741 C00030459	0 / 1
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741 C00030742	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003741 C00019308	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003741 C00030459	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003741 C00029724	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003741 C00030459	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003741 C00030459	11 / 10
P08047	Transcription factor Sp1	Unclassified protein	C00019308 C00030459	0 / 0
P15121	Aldose reductase	Enzyme	C00003741 C00030742	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741 C00030459	0 / 0
P11217	Glycogen phosphorylase, muscle form	Enzyme	C00030742	1 / 1
P10586	Receptor-type tyrosine-protein phosphatase F	Receptor tyrosine-protein phosphatase	C00030742	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003741	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003741	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003741	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
O75496	Geminin	Unclassified protein	C00003741	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00003741	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003741	0 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00003741	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003741	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
P00734	Prothrombin	S1A	C00019308	4 / 2
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00030742	4 / 2
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003741	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003741	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003741	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003741	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003741	2 / 0
P17706	Tyrosine-protein phosphatase non-receptor type 2	Tyr	C00030742	0 / 1
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00030742	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003741	1 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003741
581	BAX, BCL2L4	BCL2-associated X protein	C00003741
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003741
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003741
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003741
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003741
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions