Bixa orellana
Species
KNApSAcK Entry
| Organism name | Bixa orellana |
|---|---|
| Genus | Bixa |
| Family | Bixaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Bixa orellana |
|---|---|
| Linked NCBI taxonomy ID | 66672 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Bixaceae |
|---|---|
| ID | 66670 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004328
|
Luteolin 7-sulfate
|
No. 51 | No. 15 |
|
||||
|
C00004428
|
8-Hydroxyluteolin 7-sulfate
|
No. 51 | No. 15 |
|
||||
|
C00004197
|
Apigenin 7-sulfate
|
No. 51 | No. 15 |
|
||||
|
C00023115
|
Methyl 8'-apo-beta-carotenoate
|
No. 131 | No. 59 |
|
||||
|
C00023120
|
Methyl apo-8'-lycopenoate
|
No. 575 |
|
|||||
|
C00023106
|
Methyl apo-6'-lycopenoate
|
No. 575 |
|
|||||
|
C00023149
|
Apo-8'-bixinal
|
No. 2031 |
|
|||||
|
C00023151
|
Apo-10'-bixinal
|
No. 2031 |
|
|||||
|
C00023147
|
Methyl (9Z)-6'-oxo-6,5'-diapocaroten-6-oate
|
No. 2563 | No. 38 |
|
||||
|
C00023148
|
Methyl bixin
/ 9-cis-6,6'-Diapo-psi,psi-carotenedioic acid dimethyl ester |
No. 2563 | No. 38 |
|
||||
|
C00003762
|
Bixin
|
CHEMBL1172615
CHEMBL1574943 |
C004588
|
8 / 7 / 7 | No. 2563 | No. 38 |
|
|
|
C00003782
|
Norbixin
/ diapocarotene-6,6'-dioic acid |
CHEMBL1420783
CHEMBL1602127 |
C099823
|
12 / 15 / 10 | No. 2563 | No. 38 |
|
|
|
C00023150
|
6-Geranylgeranyl 8'-methyl 6,8'-diapocarotene-6,8'-dioate
|
No. 6952 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003762 C00003782 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003762 C00003782 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003762 C00003782 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00003782 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003762 | 2 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003762 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00003782 | 5 / 3 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00003782 | 3 / 3 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00003782 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003782 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003782 | 3 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003762 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003782 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003762 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00003762 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003782 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003782 | 3 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (21)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601665 | Obesity |
P37231
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (16)
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|