Angelica dahurica var.dahurica
Species
KNApSAcK Entry
| Organism name | Angelica dahurica var.dahurica |
|---|---|
| Genus | Angelica |
| Family | Apiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Angelica |
|---|---|
| Linked NCBI taxonomy ID | 40948 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00035717
|
(+)-Oxypeucedanin
/ Oxypeucedanin hydrate |
CHEMBL454060
CHEMBL1438253 |
13 / 5 / 8 | No. 579 | No. 25 |
|
||
|
C00002453
|
Byakangelicin
/ (+)-Byakangelicin |
CHEMBL508648
|
C434685
|
5 / 2 / 0 | No. 579 | No. 25 |
|
|
|
C00030987
|
Phellopterin
|
CHEMBL452751
|
C104601
|
7 / 18 / 10 | No. 606 | No. 25 |
|
|
|
C00000575
|
Bergaptan
|
CHEMBL24171
|
C022909
|
22 / 22 / 17 | 0 / 3 | No. 1282 | No. 25 |
|
|
C00002490
|
Oxypeucedanin
|
CHEMBL510120
CHEMBL1510267 CHEMBL1609439 |
C031535
|
8 / 14 / 11 | No. 2896 | No. 25 |
|
Human Protein / Gene in interactions
41 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P56817 | Beta-secretase 1 | A1A | C00000575 C00002453 C00002490 C00030987 C00035717 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000575 C00002453 C00002490 C00035717 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000575 C00002453 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002490 C00035717 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00030987 C00035717 | 1 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002453 C00030987 | 1 / 0 |
| O75496 | Geminin | Unclassified protein | C00002490 C00035717 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000575 C00002490 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000575 C00030987 | 7 / 3 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000575 | 3 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002490 | 3 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | C00000575 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000575 | 0 / 1 |
| P37840 | Alpha-synuclein | Unclassified protein | C00030987 | 4 / 2 |
| P16389 | Potassium voltage-gated channel subfamily A member 2 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002490 | 11 / 10 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00035717 | 2 / 2 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000575 | 0 / 0 |
| P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00030987 | 1 / 2 |
| P17658 | Potassium voltage-gated channel subfamily A member 6 | K | C00000575 | 0 / 0 |
| P20813 | Cytochrome P450 2B6 | Cytochrome P450 2B6 | C00000575 | 1 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00035717 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00035717 | 0 / 0 |
| P22001 | Potassium voltage-gated channel subfamily A member 3 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| P48547 | Potassium voltage-gated channel subfamily C member 1 | K | C00000575 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000575 | 3 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000575 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000575 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00035717 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00035717 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00030987 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000575 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000575 | 3 / 4 |
| P22460 | Potassium voltage-gated channel subfamily A member 5 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00035717 | 0 / 0 |
| Q09470 | Potassium voltage-gated channel subfamily A member 1 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002490 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002453 | 1 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00035717 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00035717 | 1 / 4 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000575 | 1 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (52)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
| #612240 | Atrial fibrillation, familial, 7; atfb7 |
P22460
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #614546 | Efavirenz, poor metabolism of |
P20813
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #160120 | Episodic ataxia, type 1; ea1 |
Q09470
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (42)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00101 | Other phagocyte defects |
P11413
(related)
|
| H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00731 | Atrial fibrillation |
P22460
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00749 | Episodic ataxias |
Q09470
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|