PCIDB

Hypericum maculatum

Species

KNApSAcK Entry

Organism name Hypericum maculatum
Genus Hypericum
Family Hypericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hypericum maculatum
Linked NCBI taxonomy ID 269006
Linked level species

Family

Family in NCBI taxonomy Hypericaceae
ID 629714

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00006431 External link 512 3,8''-Biapigenin
CHEMBL515252
21 / 16 / 12 No. 34 No. 18

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00006431 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00006431 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00006431 0 / 0
P06746 DNA polymerase beta Enzyme C00006431 0 / 0
P04062 Glucosylceramidase Enzyme C00006431 6 / 4
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00006431 0 / 0
P54132 Bloom syndrome protein Enzyme C00006431 1 / 2
P39748 Flap endonuclease 1 Enzyme C00006431 0 / 0
O75496 Geminin Unclassified protein C00006431 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00006431 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00006431 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00006431 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00006431 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00006431 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00006431 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00006431 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00006431 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00006431 0 / 0
P63165 Small ubiquitin-related modifier 1 Unclassified protein C00006431 1 / 1
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00006431 2 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00006431 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#613705 Orofacial cleft 10; ofc10 P63165
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00516 Isolated orofacial clefts P63165 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)