| Organism name | Leucanthemopsis pulverulenta | 
|---|---|
| Genus | Leucanthemopsis | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Leucanthemopsis | 
|---|---|
| Linked NCBI taxonomy ID | 133252 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00012188   | Hispanolide | No. 107 | No. 38 |   | ||||
| C00011770   | Pulverulide | No. 107 | No. 38 |   | ||||
| C00020796   | Epiligustrin | No. 306 | No. 38 |   | ||||
| C00000601   | (+)-Sesamin | CHEMBL43469 CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 | C054125 | 20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |   | 
| C00020742   | (-)-Zafronic acid methyl ester | No. 1799 |   | |||||
| C00020743   | [1R-(1alpha,4beta,4abeta,6alpha,8aalpha)]-6-(Acetyloxy)-4-ethoxy-1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 1799 |   | |||||
| C00020741   | 2-Acetylzafronic acid | No. 1799 |   | |||||
| C00020745   | [1R-(1alpha,4beta,4abeta,6alpha,8aalpha)]-4-Ethoxy-1,2,3,4,4a,5,6,8a-octahydro-6-hydroxy-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 1799 |   | |||||
| C00020748   | [1R-(1alpha,4alpha,4aalpha,6alpha,8aalpha)]-1,2,3,4,4a,5,6,8a-Octahydro-4,6-dihydroxy-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 1799 |   | |||||
| C00020747   | [1R-(1alpha,4alpha,4aalpha,6alpha,8aalpha)]-6-(Acetyloxy)-1,2,3,4,4a,5,6,8a-octahydro-4-hydroxy-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 1799 |   | |||||
| C00020746   | [1R-(1alpha,4abeta,6alpha,8aalpha)]-1,2,4a,5,6,8a-Hexahydro-6-hydroxy-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 3254 |   | |||||
| C00020749   | [1R-(1alpha,4aalpha,6alpha,8aalpha)]-6-(Acetyloxy)-1,2,4a,5,6,8a-hexahydro-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 3254 |   | |||||
| C00020744   | [1R-(1alpha,4abeta,6alpha,8aalpha)]-6-(Acetyloxy)-1,2,4a,5,6,8a-hexahydro-4,7-dimethyl-a-methylene-1-naphthaleneacetic acid methyl ester | No. 3254 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 | 1 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 | 4 / 1 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 | 0 / 1 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 | 2 / 3 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 | 2 / 0 | 
| O75496 | Geminin | Unclassified protein | C00000601 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 | 7 / 3 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 | 2 / 2 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 | 0 / 0 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 | 1 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) Q13148 (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) |