| Organism name | Polygonum ferrugineum | 
|---|---|
| Genus | Polygonum | 
| Family | Polygonaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Polygonum | 
|---|---|
| Linked NCBI taxonomy ID | 46786 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Polygonaceae | 
|---|---|
| ID | 3615 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | eudicotyledons | 
|---|---|
| ID | 71240 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00008144   | Pinostrobin / (-)-Pinostrobin / (2S)-Pinocembrin / (-)-(2S)-Pinocembrin | CHEMBL254613 | 1 / 2 / 0 | No. 25 | No. 14 |   | ||
| C00006959   | Pashanone | No. 79 |   | |||||
| C00006936   | Flavokawin B | CHEMBL104255 | 19 / 31 / 55 | No. 79 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00006936 C00008144 | 2 / 0 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00006936 | 1 / 2 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00006936 | 1 / 1 | 
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00006936 | 1 / 4 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00006936 | 2 / 3 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00006936 | 2 / 0 | 
| O75496 | Geminin | Unclassified protein | C00006936 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00006936 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00006936 | 7 / 3 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00006936 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00006936 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00006936 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00006936 | 3 / 3 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00006936 | 7 / 37 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00006936 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00006936 | 0 / 1 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00006936 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00006936 | 4 / 3 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00006936 | 1 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #208900 | Ataxia-telangiectasia; at | Q13315 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #614490 | Blood group, junior system; jr | Q9UNQ0 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #133239 | Esophageal cancer | P04637 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | Q9UNQ0 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) Q13315 (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00033 | Adrenal carcinoma | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) P08684 (marker) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00064 | Ataxia telangiectasia (AT) | Q13315
                            (related) | 
| H00094 | DNA repair defects | Q13315
                            (related) | 
| H00848 | Ataxia with ocular apraxia (AOA) | Q13315
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) |