PCIDB

Hylocereus purpusii

Species

KNApSAcK Entry

Organism name Hylocereus purpusii
Genus Hylocereus
Family Cactaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hylocereus
Linked NCBI taxonomy ID 154422
Linked level genus

Family

Family in NCBI taxonomy Cactaceae
ID 3593

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00034629 External link 512 Phyllocactin II
No. 763 No. 71
C00034628 External link 512 Phyllocactin
No. 763 No. 71
C00034541 External link 512 Hylocerenin
/ (15S)-Hylocerenin
No. 763 No. 71
C00034383 External link 512 2'-O-Apiosylphyllocactin
No. 763 No. 71
C00034376 External link 512 2'-(5''-O-E-Feruloylapiosyl)phyllocactin
No. 2277 No. 71
C00034375 External link 512 2'-(5''-O-E-Sinapoylapiosyl)betanin
No. 2277 No. 71
C00007291 External link 512 Betaine
CHEMBL95889
CHEMBL1182
D001622
10 / 5 / 5 4 / 11 No. 5024

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007291 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00007291 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007291 0 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00007291 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007291 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007291 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007291 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00007291 0 / 1
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein C00007291 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00007291 0 / 0

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
635 BHMT, BHMT1 betaine--homocysteine S-methyltransferase (EC:2.1.1.5) C00007291
2157 F8, AHF, DXS1253E, F8B, F8C, FVIII, HEMA coagulation factor VIII, procoagulant component C00007291
2158 F9, FIX, HEMB, P19, PTC, THPH8 coagulation factor IX (EC:3.4.21.22) C00007291
6584 SLC22A5, CDSP, OCTN2, OCTN2VT solute carrier family 22 (organic cation/carnitine transporter), member 5 C00007291

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

11 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003711 Demyelinating Diseases C00007291
D056486 Drug-Induced Liver Injury C00007291
D005235 Fatty Liver, Alcoholic C00007291
D006712 Homocystinuria C00007291
D008106 Liver Cirrhosis, Experimental C00007291
D008113 Liver Neoplasms C00007291
D008569 Memory Disorders C00007291
D008661 Metabolism, Inborn Errors C00007291
D009203 Myocardial Infarction C00007291
D009436 Neural Tube Defects C00007291
D013610 Tachycardia C00007291