Species

KNApSAcK Entry

Organism name Berchemia discolor
Genus Berchemia
Family Rhamnaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Berchemia discolor
Linked NCBI taxonomy ID 72168
Linked level species

Family

Family in NCBI taxonomy Rhamnaceae
ID 3608

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009575 External link 512 Amorphigenin
/ 8'-Hydroxyrotenone
CHEMBL465552
CHEMBL1447847
CHEMBL1490209
C049148
7 / 8 / 12 1 / 0 No. 281 No. 15
C00009738 External link 512 Nitidulin
CHEMBL518081
No. 352 No. 15

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00009575 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00009575 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00009575 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00009575 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00009575 4 / 3
O00255 Menin Unclassified protein C00009575 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00009575 1 / 2

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00009575

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (12)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)