Aspergillus sp. FO-4282
Species
KNApSAcK Entry
| Organism name | Aspergillus sp. FO-4282 |
|---|---|
| Genus | Aspergillus |
| Family | Trichocomaceae |
| Kingdom | Fungi |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Aspergillus |
|---|---|
| Linked NCBI taxonomy ID | 5052 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Aspergillaceae |
|---|---|
| ID | 1131492 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00011359
|
Aspochalasin C
|
CHEMBL519431
CHEMBL479328 CHEMBL1981103 |
27 / 28 / 22 | No. 593 |
|
|||
|
C00011360
|
Aspochalasin D
|
CHEMBL519431
CHEMBL479328 CHEMBL1981103 |
27 / 28 / 22 | No. 593 |
|
|||
|
C00016394
|
Aspochalasin F
|
No. 593 |
|
|||||
|
C00016395
|
Aspochalasin G
|
No. 593 |
|
|||||
|
C00016018
|
Dehydrocurvularin
/ Dehydro-curvularin / trans-Dehydrocurvularin / alpha,beta-Dehydrocurvularin |
CHEMBL482050
CHEMBL520014 CHEMBL1643635 |
C013914
|
21 / 19 / 20 | No. 871 |
|
Human Protein / Gene in interactions
34 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00011359 C00011360 C00016018 | 4 / 3 |
| Q99700 | Ataxin-2 | Unclassified protein | C00011359 C00011360 C00016018 | 1 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00011359 C00011360 C00016018 | 1 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00011359 C00011360 C00016018 | 0 / 0 |
| O75030 | Microphthalmia-associated transcription factor | Unclassified protein | C00011359 C00011360 C00016018 | 4 / 4 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00011359 C00011360 C00016018 | 2 / 3 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00011359 C00011360 C00016018 | 1 / 1 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00011359 C00011360 C00016018 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00011359 C00011360 C00016018 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00011359 C00011360 C00016018 | 1 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00011359 C00011360 C00016018 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00011359 C00011360 C00016018 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00011359 C00011360 C00016018 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00011359 C00011360 C00016018 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00011359 C00011360 | 4 / 2 |
| Q9Y2T6 | G-protein coupled receptor 55 | Lysophosphatidylinositol receptor | C00011359 C00011360 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00011359 C00011360 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00011359 C00011360 | 2 / 5 |
| P21453 | Sphingosine 1-phosphate receptor 1 | EDG receptor | C00011359 C00011360 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00011359 C00011360 | 0 / 0 |
| O95977 | Sphingosine 1-phosphate receptor 4 | EDG receptor | C00011359 C00011360 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00011359 C00011360 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00011359 C00011360 | 1 / 2 |
| Q9GZV3 | High affinity choline transporter 1 | Choline Na-symporter | C00011359 C00011360 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00011359 C00011360 | 2 / 0 |
| P17861 | X-box-binding protein 1 | Unclassified protein | C00011359 C00011360 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00011359 C00011360 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00016018 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00016018 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00016018 | 1 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00016018 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00016018 | 1 / 4 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00016018 | 0 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00016018 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (31)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
O75030
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #143100 | Huntington disease; hd |
P42858
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #614456 | Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 |
O75030
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #158580 | Neuronopathy, distal hereditary motor, type viia; hmn7a |
Q9GZV3
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #103500 | Tietz syndrome |
O75030
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #193510 | Waardenburg syndrome, type 2a; ws2a |
O75030
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (30)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00038 | Malignant melanoma |
O75030
(related)
O75030 (marker) |
| H00169 | Ocular albinism |
O75030
(related)
|
| H00759 | Waardenburg syndrome (WS) |
O75030
(related)
|
| H01187 | Tietz syndrome |
O75030
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|