PCIDB

Jurinea alata

Species

KNApSAcK Entry

Organism name Jurinea alata
Genus Jurinea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Jurinea
Linked NCBI taxonomy ID 41593
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003208 External link 512 Alatolide
CHEMBL405877
CHEMBL1882112
CHEMBL1993440
C006438
10 / 9 / 8 No. 211 No. 38
C00000609 External link 512 (-)-Arctigenin
CHEMBL369142
CHEMBL435734
CHEMBL1966556
C071942
13 / 7 / 6 No. 223 No. 21

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000609 C00003208 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000609 C00003208 0 / 0
Q99700 Ataxin-2 Unclassified protein C00000609 C00003208 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000609 C00003208 2 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000609 1 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00003208 0 / 0
O75496 Geminin Unclassified protein C00003208 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00000609 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00003208 4 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000609 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00003208 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00000609 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000609 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00000609 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000609 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000609 0 / 1
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00000609 1 / 1
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003208 0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00003208 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#114500 Colorectal cancer; crc P84022
Q14191
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (13)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)