Species

KNApSAcK Entry

Organism name Fusarium sp.
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Fusarium sp.
Linked NCBI taxonomy ID 29916
Linked level species

Family

Family in NCBI taxonomy Nectriaceae
ID 110618

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00012613 External link 512 Solaniol
/ Neosolaniol
/ Neozolaniol
/ (3alpha,4beta,8alpha)-12,13-Epoxy-trichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate
CHEMBL358485
CHEMBL422680
CHEMBL345149
CHEMBL156831
No. 539
C00018907 External link 512 Enniatin A1
No. 859
C00018905 External link 512 Enniatin B
CHEMBL469036
19 / 22 / 23 No. 859
C00018906 External link 512 Enniatin B1
CHEMBL446318
No. 859
C00018754 External link 512 Ascochlorin
/ LL-Z1272gamma
/ 2,4-Dihydroxy-3-substituted-5-chloroorcylaldehyde
CHEMBL132623
6 / 9 / 8 No. 962
C00012644 External link 512 Isotrichodermol
/ 3-Hydroxytrichothecene
No. 1262
C00034230 External link 512 Selenocysteine
CHEMBL109962
CHEMBL2111732
No. 2513
C00034229 External link 512 Selenocysteic acid
No. 8052

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75469 Nuclear receptor subfamily 1 group I member 2 NR1I2 C00018754 0 / 0
Q99700 Ataxin-2 Unclassified protein C00018905 1 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00018905 1 / 4
P42858 Huntingtin Unclassified protein C00018905 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00018905 2 / 0
O75496 Geminin Unclassified protein C00018905 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00018905 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00018754 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00018905 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00018905 7 / 3
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00018754 5 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00018905 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00018905 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00018905 0 / 0
P03372 Estrogen receptor NR3A1 C00018754 1 / 1
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00018905 1 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00018905 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00018905 0 / 0
P10275 Androgen receptor NR3C4 C00018754 3 / 4
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00018754 0 / 0
O00167 Eyes absent homolog 2 Enzyme C00018905 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00018905 1 / 0
O00255 Menin Unclassified protein C00018905 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00018905 1 / 2
P01215 Glycoprotein hormones alpha chain Unclassified protein C00018905 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (30)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#208900 Ataxia-telangiectasia; at Q13315
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143100 Huntington disease; hd P42858
#145000 Hyperparathyroidism 1; hrpt1 O00255
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P37231
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (31)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)