Species

KNApSAcK Entry

Organism name Uvaria dulcis
Genus Uvaria
Family Annonaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Uvaria dulcis
Linked NCBI taxonomy ID 174962
Linked level species

Family

Family in NCBI taxonomy Annonaceae
ID 22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036451 External link 512 2',3'-Dihydroxy-4',6'-dimethoxychalcone
CHEMBL1446527
13 / 17 / 11 No. 79
C00014598 External link 512 2',3'-Dihydroxy-4',6'-dimethoxydihydrochalcone
No. 90 No. 13

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00036451 0 / 0
Q99700 Ataxin-2 Unclassified protein C00036451 1 / 1
P11473 Vitamin D3 receptor NR1I1 C00036451 2 / 3
O75496 Geminin Unclassified protein C00036451 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00036451 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00036451 1 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00036451 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00036451 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00036451 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00036451 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00036451 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00036451 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00036451 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#600274 Frontotemporal dementia; ftd P10636
#174800 Mccune-albright syndrome; mas P63092
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (11)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)