Species

KNApSAcK Entry

Organism name Nocardia sp. No. C-15003 (N-1)
Genus Nocardia
Family Nocardiaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Nocardia
Linked NCBI taxonomy ID 1817
Linked level genus

Family

Family in NCBI taxonomy Nocardiaceae
ID 85025

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018269 External link 512 NSC 292222
/ Ansamitosin P 3
/ Ansamitocin P 3
/ Antibiotic C 15003P3
/ Maytansinol isobutyrate
CHEMBL294181
CHEMBL359364
CHEMBL507305
CHEMBL442610
CHEMBL1553400
7 / 5 / 5 No. 1194
C00018270 External link 512 Ansamitocin P 3'
/ Maytansinol butyrate
/ Antibiotic C 15003P3'
No. 1194
C00018271 External link 512 NSC 292223
/ Ansamitocin P 4
/ Antibiotic C 15003P4
/ Maytansinol isovalerate
No. 1194

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018269 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00018269 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018269 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00018269 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018269 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018269 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018269 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)