Streptomyces narbonenensis var. josamyceticus nov. var. A 204-P2


Species

KNApSAcK Entry

Organism name Streptomyces narbonenensis var. josamyceticus nov. var. A 204-P2
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018736 External link 512 EN 141
/ Jomybel
/ Josamina
/ Iosalide
/ Josacine
/ Vilprafen
/ Josamycin
/ Wilprafen
/ Turimycin A5
/ Kitasamycin A3
/ Antibiotic YL 704A3
CHEMBL329011
CHEMBL224436
CHEMBL1326015
CHEMBL1671903
CHEMBL1995525
CHEMBL2361089
D015570
9 / 4 / 5 2 / 2 No. 180

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018736 1 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00018736 2 / 2
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00018736 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018736 0 / 1
P55085 Proteinase-activated receptor 2 Protease-activated receptor C00018736 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00018736 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018736 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018736 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018736 0 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1378 CR1, C3BR, C4BR, CD35, KN complement component (3b/4b) receptor 1 (Knops blood group) C00018736
3689 ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) C00018736

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613688 Long qt syndrome 2; lqt2 Q12809
#609620 Short qt syndrome 1; sqt1 Q12809

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003875 Drug Eruptions C00018736
D014581 Urticaria C00018736