Species

KNApSAcK Entry

Organism name Stylissa carteri
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stylissa carteri
Linked NCBI taxonomy ID 279588
Linked level species

Family

Family in NCBI taxonomy Axinellidae
ID 45118

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00021689 External link 512 Hymenin
/ Epiparthenin
CHEMBL312004
CHEMBL401149
CHEMBL1869439
10 / 5 / 4 No. 495 No. 38
C00049340 External link 512 (Z)-3-Bromohymenialdisine
CHEMBL480350
1 / 0 / 0 No. 1755
C00049402 External link 512 Spongiacidin A
CHEMBL480350
1 / 0 / 0 No. 1755
C00049339 External link 512 (E)-Debromohymenialdisine
CHEMBL255465
CHEMBL1221876
9 / 8 / 2 No. 1755
C00049342 External link 512 (Z)-Hymenialdisine
CHEMBL359106
CHEMBL361708
22 / 8 / 4 No. 1755
C00049341 External link 512 (Z)-Debromohymenialdisine
CHEMBL255465
CHEMBL1221876
9 / 8 / 2 No. 1755
C00028776 External link 512 Oroidin
CHEMBL397591
C077209
3 / 3 / 1 No. 2659
C00049370 External link 512 Debromohymenin
No. 7084
C00041894 External link 512 Stevensine
CHEMBL464097
2 / 0 / 0 No. 8299

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00049339 C00049340 C00049341 C00049342 C00049402 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00028776 C00049339 C00049341 C00049342 0 / 0
P04049 RAF proto-oncogene serine/threonine-protein kinase Raf C00028776 C00049339 C00049341 C00049342 2 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00028776 C00049339 C00049341 C00049342 1 / 1
P68400 Casein kinase II subunit alpha Ck2 C00049339 C00049341 C00049342 0 / 0
O96017 Serine/threonine-protein kinase Chk2 Rad53 C00049339 C00049341 C00049342 4 / 1
P05771 Protein kinase C beta type Alpha C00049339 C00049341 C00049342 0 / 0
P17252 Protein kinase C alpha type Alpha C00049339 C00049341 C00049342 0 / 0
P48730 Casein kinase I isoform delta Ck1 C00049339 C00049341 C00049342 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00021689 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00049342 0 / 0
P24864 G1/S-specific cyclin-E1 Other cytosolic protein C00049342 0 / 2
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00041894 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00021689 2 / 0
O75496 Geminin Unclassified protein C00021689 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00041894 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00049342 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00049342 0 / 0
Q99683 Mitogen-activated protein kinase kinase kinase 5 Ste11 C00049342 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00021689 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00021689 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00049342 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00049342 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00049342 0 / 0
O15226 NF-kappa-B-repressing factor Transcription Factor C00049342 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00021689 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00021689 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00049342 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00049342 0 / 0
P20248 Cyclin-A2 Other cytosolic protein C00049342 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00049342 0 / 0
Q99700 Ataxin-2 Unclassified protein C00021689 1 / 1
P01215 Glycoprotein hormones alpha chain Unclassified protein C00021689 0 / 3
P51531 Probable global transcription activator SNF2L2 Unclassified protein C00021689 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#114480 Breast cancer O96017
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 O75874
#611554 Leopard syndrome 2 P04049
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#601358 Nicolaides-baraitser syndrome; ncbrs P51531
#611553 Noonan syndrome 5; ns5 P04049
#259500 Osteogenic sarcoma O96017
#176807 Prostate cancer O96017
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (8)

KEGG name UniProt
H00881 Li-Fraumeni syndrome O96017 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00018 Gastric cancer P24864 (related)
H00055 Laryngeal cancer P24864 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)