PCIDB

Ervatamia coronaria

Species

KNApSAcK Entry

Organism name Ervatamia coronaria
Genus Ervatamia
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tabernaemontana divaricata
Linked NCBI taxonomy ID 52861
Linked level species

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00024582 External link 512 Modestanine
/ Modestamine
/ Deoxoapodine
/ Demethoxyvandrikine
No. 61 No. 4
C00042577 External link 512 Hecubine
No. 502 No. 4
C00024538 External link 512 Hyderabadine
No. 828
C00024533 External link 512 Ervatinine
/ (+)-Ervatinine
No. 828
C00024619 External link 512 Voaphyllin
/ Conoflorin
/ Conoflorine
/ Voaphylline
/ (+)-Conoflorine
/ (+)-Voaphylline
CHEMBL496674
No. 828
C00024601 External link 512 Stapfinine
/ 5-hydroxyvoaphylline
No. 828
C00025859 External link 512 Dregamine
/ (-)-Dregamine
/ 20-Epitabernemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771
C00024470 External link 512 Mehranine
/ (+)-Mehranine
No. 2780

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00025859 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00025859 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00025859 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00025859 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00025859 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00025859 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00025859 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025859 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00025859 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)