Kopsia arborea
Species
KNApSAcK Entry
| Organism name | Kopsia arborea |
|---|---|
| Genus | Kopsia |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Kopsia arborea |
|---|---|
| Linked NCBI taxonomy ID | 453901 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (25)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00038182
|
19(S)-Methoxytubotaiwine
/ (+)-19(S)-Methoxytubotaiwine |
CHEMBL251650
CHEMBL400176 |
No. 61 | No. 4 |
|
|||
|
C00038181
|
19(R)-Methoxytubotaiwine
|
CHEMBL251650
CHEMBL400176 |
No. 61 | No. 4 |
|
|||
|
C00047264
|
Kopsiyunnanine D
/ (-)-Kopsiyunnanine D |
CHEMBL564146
|
No. 502 | No. 4 |
|
|||
|
C00034178
|
Prunifoline D
/ (+)-Prunifoline D |
No. 527 |
|
|||||
|
C00034179
|
Prunifoline F
/ Flavisiamine C / (+)-Prunifoline F / 2-Methoxyflavisiamine A |
No. 527 |
|
|||||
|
C00039569
|
Kopsamidine B
|
No. 571 |
|
|||||
|
C00034056
|
Methyl-11,12-dimethoxychanofruticosinate
|
No. 880 |
|
|||||
|
C00034057
|
Methyl-12-methoxychanofruticosinate
|
No. 880 |
|
|||||
|
C00024580
|
Methyl 11,12-methylenedioxychanofruticosinate
|
No. 880 |
|
|||||
|
C00039934
|
Paucidactine C
/ (+)-Paucidactine C |
No. 937 |
|
|||||
|
C00039591
|
Kopsinidine B
/ (+)-Kopsinidine B |
No. 937 |
|
|||||
|
C00039590
|
Kopsinidine A
/ (-)-Kopsinidine A |
No. 937 |
|
|||||
|
C00038489
|
Arbophylline
/ (+)-Arbophylline |
No. 946 |
|
|||||
|
C00040153
|
Rhazinaline
|
No. 1217 |
|
|||||
|
C00039953
|
Pericine N-oxide
|
No. 1476 |
|
|||||
|
C00040617
|
Valparicine
|
CHEMBL251682
|
No. 1673 |
|
||||
|
C00039568
|
Kopsamidine A
/ (+)-Kopsamidine A |
No. 2209 |
|
|||||
|
C00047261
|
Kopsiyunnanine C1
/ (-)-Kopsiyunnanine C1 |
CHEMBL557810
|
No. 3045 |
|
||||
|
C00047263
|
Kopsiyunnanine C3
/ (-)-Kopsiyunnanine C3 |
CHEMBL558634
|
No. 3045 |
|
||||
|
C00047262
|
Kopsiyunnanine C2
/ (-)-Kopsiyunnanine C2 |
CHEMBL564900
|
No. 3045 |
|
||||
|
C00038487
|
Arboflorine
/ (+)-Arboflorine |
No. 3568 |
|
|||||
|
C00038491
|
Arboricinine
/ (-)-Arboricinine |
CHEMBL251688
|
No. 3568 |
|
||||
|
C00026581
|
Mersicarpine
|
No. 3903 |
|
|||||
|
C00038490
|
Arboricine
|
CHEMBL1410733
|
6 / 17 / 17 | No. 4353 |
|
|||
|
C00038488
|
Arboloscine
/ (+)-Arboloscine |
CHEMBL400902
|
No. 6861 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | C00038490 | 4 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00038490 | 11 / 10 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00038490 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00038490 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00038490 | 0 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00038490 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (17)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
KEGG DISEASE (17)
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|