Radix pareira brava
Metabolite list (2)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00025602
|
l-Curine
/ (-)-Curine / l-Bebeerine / Aristolochine / (-)-Bebeerine / Aristolochine(C36 alkaloid) |
CHEMBL1169627
|
13 / 6 / 5 | No. 10 | No. 4 |
|
||
|
C00027385
|
Isococlaurine
/ R-(+)-Isococlaurine |
No. 253 | No. 4 |
|
Human Protein / Gene in interactions
13 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00025602 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00025602 | 1 / 1 |
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | C00025602 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00025602 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00025602 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00025602 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025602 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025602 | 4 / 3 |
| O43603 | Galanin receptor type 2 | Galanin receptor | C00025602 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00025602 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00025602 | 0 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00025602 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143100 | Huntington disease; hd |
P42858
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|