Species

KNApSAcK Entry

Organism name Abuta grisebachii Triana & Planch
Genus Abuta
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Abuta
Linked NCBI taxonomy ID 341012
Linked level genus

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00026007 External link 512 Peinamine
/ (-)-2-Demethylberbamine
CHEMBL510273
No. 10 No. 4
C00025957 External link 512 O7-Demethyl-N-methylpeinamine
/ N-Methyl-7-O-demethylpeinamine
CHEMBL500609
CHEMBL452895
CHEMBL492604
CHEMBL1976284
No. 10 No. 4
C00025936 External link 512 Macolidine
CHEMBL504525
CHEMBL508781
6 / 2 / 3 No. 10 No. 4
C00025880 External link 512 Magnolin
/ Grisabutine
CHEMBL1187468
No. 89 No. 4
C00025611 External link 512 Grisabine
/ (-)-Grisabine
/ 1-Epicuspidaline
CHEMBL1186148
No. 89 No. 4

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00025936 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00025936 0 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00025936 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00025936 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00025936 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025936 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)