Species

KNApSAcK Entry

Organism name Methanococcus voltae
Genus Methanococcus
Family Methanococcaceae
Kingdom Euryarchaeota

NCBI taxonomy

Entry

Linked NCBI taxonomy name Methanococcus voltae
Linked NCBI taxonomy ID 2188
Linked level species

Family

Family in NCBI taxonomy Methanococcaceae
ID 2183

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Archaea
ID 2157

Plant class

Plant class
ID

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000773 External link 512 alpha-Ketosuberate
/ 2-Oxooctanedioic acid
/ alpha-Ketosuberic acid
C062868
No. 2414
C00000769 External link 512 alpha-Oxoglutaric acid
/ alpha-Ketoglutaric acid
CHEMBL1686
C029743
13 / 6 / 7 8 / 0 No. 2414
C00000770 External link 512 2-Oxoadipic acid
/ alpha-Ketoadipate
/ alpha-Ketoadipic acid
C001918
No. 2414
C00000771 External link 512 alpha-Oxopimelic acid
/ alpha-Ketopimelic acid
CHEMBL185075
1 / 1 / 0 No. 2414
C00000768 External link 512 N-(7-Mercaptoheptanoyl)-L-threonine
No. 4447
C00000772 External link 512 7-Thioheptanoic acid
/ 7-Mercaptoheptanoic acid
C062867
No. 7893

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9H6Z9 Egl nine homolog 3 Enzyme C00000769 0 / 0
Q9Y694 Solute carrier family 22 member 7 Unclassified protein C00000769 0 / 0
P08183 Multidrug resistance protein 1 drug C00000769 1 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00000769 1 / 1
P13674 Prolyl 4-hydroxylase subunit alpha-1 Enzyme C00000769 0 / 0
Q96KS0 Egl nine homolog 2 Enzyme C00000769 0 / 0
Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor Enzyme C00000769 0 / 0
Q8TCC7 Solute carrier family 22 member 8 Antiporter C00000769 0 / 0
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00000769 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00000769 0 / 0
Q86XE5 Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Enzyme C00000771 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000769 0 / 0
P10275 Androgen receptor NR3C4 C00000769 3 / 4
O76082 Solute carrier family 22 member 5 Unclassified protein C00000769 1 / 2

8 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8424 BBOX1, BBH, BBOX, G-BBH, gamma-BBH butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (EC:1.14.11.1) C00000769
728294 D2HGDH, D2HGD D-2-hydroxyglutarate dehydrogenase (EC:1.1.99.-) C00000769
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00000769
8290 HIST3H3, H3.4, H3/g, H3FT, H3t histone cluster 3, H3 C00000769
55818 KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA lysine (K)-specific demethylase 3A C00000769
54681 P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) C00000769
9356 SLC22A6, HOAT1, OAT1, PAHT, ROAT1 solute carrier family 22 (organic anion transporter), member 6 C00000769
7428 VHL, HRCA1, RCA1, VHL1, pVHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase C00000769

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#212140 Carnitine deficiency, systemic primary; cdsp O76082
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#613616 Hyperoxaluria, primary, type iii; hp3 Q86XE5
#612244 Inflammatory bowel disease 13; ibd13 P08183
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (7)

KEGG name UniProt
H00286 Crohn's disease O76082 (related)
H00525 Disorders of fatty-acid oxidation O76082 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00236 Congenital polycythemia Q9GZT9 (related)