PCIDB

Glaucium flavum Crantz.

Species

KNApSAcK Entry

Organism name Glaucium flavum Crantz.
Genus Glaucium
Family Papaveraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Glaucium
Linked NCBI taxonomy ID 56852
Linked level genus

Family

Family in NCBI taxonomy Papaveraceae
ID 3465

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00026144 External link 512 Sinactine
/ Tetrahydroepiberberine
No. 37 No. 4
C00027457 External link 512 Oxoglaucine
/ O-Methylatheroline
CHEMBL470881
C111587
25 / 27 / 24 No. 74
C00028139 External link 512 Dehydroglaucine
No. 439

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00027457 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00027457 0 / 0
P06746 DNA polymerase beta Enzyme C00027457 0 / 0
P29466 Caspase-1 C14 C00027457 0 / 0
Q92793 CREB-binding protein Enzyme C00027457 1 / 1
P02545 Prelamin-A/C Unclassified protein C00027457 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00027457 0 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00027457 1 / 0
P39748 Flap endonuclease 1 Enzyme C00027457 0 / 0
P42858 Huntingtin Unclassified protein C00027457 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00027457 2 / 0
O75496 Geminin Unclassified protein C00027457 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00027457 1 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00027457 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00027457 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00027457 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00027457 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00027457 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00027457 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00027457 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00027457 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00027457 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00027457 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00027457 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00027457 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#180849 Rubinstein-taybi syndrome 1; rsts1 Q92793
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (24)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00504 Rubinstein-Taybi syndrome Q92793 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)