Vitex negundo
Species
KNApSAcK Entry
| Organism name | Vitex negundo |
|---|---|
| Genus | Vitex |
| Family | Labiatae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Vitex negundo |
|---|---|
| Linked NCBI taxonomy ID | 361442 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (30)
| Species | Activity |
|---|---|
| Vitex negundo L. | Alterative |
| Vitex negundo L. | Analgesic |
| Vitex negundo L. | Antiandrogenic |
| Vitex negundo L. | Antibacterial |
| Vitex negundo L. | Antiedemic |
| Vitex negundo L. | Antiinflammatory |
| Vitex negundo L. | Antipyretic |
| Vitex negundo L. | Antiseptic |
| Vitex negundo L. | Antitussive |
| Vitex negundo L. | Astringent |
| Vitex negundo L. | Bronchodilator |
| Vitex negundo L. | Carminative |
| Vitex negundo L. | CNS-Depressant |
| Vitex negundo L. | Demulcent |
| Vitex negundo L. | Detoxicant |
| Vitex negundo L. | Diaphoretic |
| Vitex negundo L. | Discutient |
| Vitex negundo L. | Diuretic |
| Vitex negundo L. | Emmenagogue |
| Vitex negundo L. | Expectorant |
| Vitex negundo L. | Hepatoprotective |
| Vitex negundo L. | Insecticide |
| Vitex negundo L. | Lactagogue |
| Vitex negundo L. | Larvicide |
| Vitex negundo L. | Nervine |
| Vitex negundo L. | Sedative |
| Vitex negundo L. | Tonic |
| Vitex negundo L. | Tranquilizer |
| Vitex negundo L. | Vermifuge |
| Vitex negundo L. | Vulnerary |
Metabolite list (28)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006403
|
5,7-Dihydroxy-8-3',4',5'-tetramethoxyflavone 5-O-rhamnoside-6-C-glucoside
|
No. 1 | No. 15 |
|
||||
|
C00005770
|
Mearnsetin 3-galactosyl-(1->4)-galactoside
|
No. 1 | No. 15 |
|
||||
|
C00005684
|
Artemetin 5-glucosyl-(1->4)-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00004440
|
5,7,3'-Trihydroxy-6.8,4'-trimethoxyflavone 5-(6''-acetylglucoside)
|
No. 2 | No. 15 |
|
||||
|
C00003930
|
Acerosin
/ 3',5,7-Trihydroxy-4',6,8-trimethoxyflavone / 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004762
|
Mearnsetin
|
CHEMBL484633
|
No. 3 | No. 15 |
|
|||
|
C00004705
|
Casticin
/ Vitexicarpin / Quercetagetin 3,6,7,4'-tetramethyl ether / 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL452767
|
C054133
|
No. 8 | No. 15 |
|
||
|
C00006371
|
5,7-Dihydroxy-8,3',4',5'-tetramethoxyflavone 6-C-glucoside
|
No. 22 | No. 15 |
|
||||
|
C00008307
|
5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone
|
CHEMBL513290
|
No. 77 | No. 14 |
|
|||
|
C00008308
|
5,3'-Dihydroxy-7,8,4'-trimethoxyflavanone
|
No. 77 | No. 14 |
|
||||
|
C00043759
|
Negundoside
|
CHEMBL239350
CHEMBL519878 |
1 / 0 / 0 | No. 213 |
|
|||
|
C00000805
|
alpha-Pinene
|
CHEMBL442565
|
C005451
|
3 / 3 / 2 | 0 / 1 | No. 476 | No. 35 |
|
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00048229
|
Vitexdoin C
|
CHEMBL1079038
|
No. 561 |
|
||||
|
C00048231
|
Vitexdoin E
|
CHEMBL1078524
|
No. 561 |
|
||||
|
C00032060
|
Negundin A
|
No. 561 |
|
|||||
|
C00048230
|
Vitexdoin D
|
CHEMBL1078523
|
No. 561 |
|
||||
|
C00032501
|
Vitrofolal E
|
CHEMBL486412
|
No. 561 |
|
||||
|
C00032502
|
Vitrofolal F
|
CHEMBL486413
|
No. 561 |
|
||||
|
C00048228
|
Vitexdoin B
|
CHEMBL1079037
|
No. 561 |
|
||||
|
C00044011
|
Vitedoamine A
|
CHEMBL487008
|
No. 561 |
|
||||
|
C00003068
|
Agnuside
/ Buddlejoside A |
CHEMBL391454
CHEMBL483223 |
1 / 0 / 0 | No. 1380 | No. 36 |
|
||
|
C00044013
|
Vitedoin B
/ (+)-Vitedoin B |
CHEMBL505801
|
No. 2336 |
|
||||
|
C00003029
|
Camphene
|
CHEMBL506889
CHEMBL510535 |
C019286
|
No. 2460 | No. 35 |
|
||
|
C00044012
|
Vitedoin A
/ (-)-Vitedoin A |
CHEMBL487007
|
No. 2594 |
|
||||
|
C00032061
|
Negundin B
/ (-)-Negundin B |
No. 2594 |
|
|||||
|
C00048227
|
Vitexdoin A
/ (-)-Vitexdoin A |
CHEMBL1079287
|
No. 2594 |
|
||||
|
C00007205
|
(+)-Lyoniresinol
|
CHEMBL455365
CHEMBL1760594 CHEMBL1761710 |
No. 4145 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00003068 C00043759 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000805 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000805 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000805 | 3 / 2 |
| O00255 | Menin | Unclassified protein | C00003110 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003110 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (9)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|