Species

KNApSAcK Entry

Organism name Veratrum viride Ait.
Genus Veratrum
Family Melanthiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Veratrum
Linked NCBI taxonomy ID 50241
Linked level genus

Family

Family in NCBI taxonomy Melanthiaceae
ID 50362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029198 External link 512 Veramivirine
No. 265 No. 11
C00028946 External link 512 Rubijervine
CHEMBL1512978
CHEMBL1993702
5 / 2 / 3 No. 265 No. 11
C00028947 External link 512 Rubivirine
No. 265 No. 11
C00028296 External link 512 Germbudine
No. 321 No. 11
C00029202 External link 512 Veratrine
CHEMBL439496
CHEMBL451227
CHEMBL1363612
CHEMBL1710967
D014701
11 / 6 / 8 0 / 1 No. 321 No. 11
C00028667 External link 512 Neogermbudine
C052980
No. 321 No. 11
C00028300 External link 512 Germine
C100083
No. 607 No. 11
C00028298 External link 512 Germidine
C427628
No. 607 No. 11
C00028033 External link 512 Cevadine
CHEMBL507882
CHEMBL2163790
D014702
0 / 1 No. 607 No. 11
C00029203 External link 512 Veratrosine
No. 1681 No. 11
C00028870 External link 512 Pseudojervine
/ Jervine 3-O-beta-D-glucopyranoside
/ 3beta-(D-glucopyranosyloxy)-jervine
No. 3567

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00028946 C00029202 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00028946 C00029202 0 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00028946 C00029202 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00028946 C00029202 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00028946 C00029202 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00029202 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00029202 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00029202 3 / 2
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00029202 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00029202 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00029202 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (8)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
P16473 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001919 Bradycardia C00029202
D009410 Nerve Degeneration C00028033