Organism name | Myroides sp. SM1 |
---|---|
Genus | Myroides |
Family | Myroidaceae |
Kingdom | Bacteria |
Linked NCBI taxonomy name | Myroides pelagicus |
---|---|
Linked NCBI taxonomy ID | 270914 |
Linked level | species |
Family in NCBI taxonomy | Flavobacteriaceae |
---|---|
ID | 49546 |
Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
---|---|
ID | 2 |
Plant class | |
---|---|
ID |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00029948
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Methyl chlorogenate
/ Methyl 5-O-caffeoylquinate / Chlorogenic acid methyl ester |
CHEMBL416955
CHEMBL596924 CHEMBL1765881 CHEMBL1765882 CHEMBL2048503 CHEMBL2349427 |
6 / 5 / 4 | No. 314 | No. 6 |
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||
C00030117
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Deoxycholic acid
/ 3alpha,12alpha-Dihydroxy-5.beta.-cholanoic acid |
CHEMBL348338
CHEMBL412516 CHEMBL410872 CHEMBL406393 CHEMBL1609669 CHEMBL2078862 CHEMBL2092842 CHEMBL2356050 |
D003840
|
16 / 7 / 7 | 44 / 12 | No. 2182 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00030117 | 1 / 0 |
O95342 | Bile salt export pump | drug | C00030117 | 2 / 1 |
P39900 | Macrophage metalloelastase | M10A | C00029948 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00029948 | 2 / 2 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00030117 | 0 / 0 |
Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00030117 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00030117 | 0 / 1 |
Q14973 | Sodium/bile acid cotransporter | Bile acid | C00030117 | 0 / 0 |
Q12908 | Ileal sodium/bile acid cotransporter | Bile acid | C00030117 | 1 / 1 |
O75496 | Geminin | Unclassified protein | C00030117 | 0 / 0 |
P03956 | Interstitial collagenase | M10A | C00029948 | 0 / 1 |
P45452 | Collagenase 3 | M10A | C00029948 | 1 / 1 |
P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00030117 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00030117 | 0 / 0 |
P08253 | 72 kDa type IV collagenase | M10A | C00029948 | 1 / 3 |
P23467 | Receptor-type tyrosine-protein phosphatase beta | Receptor tyrosine-protein phosphatase | C00030117 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00030117 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00030117 | 0 / 1 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00030117 | 0 / 0 |
P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00030117 | 1 / 1 |
P08254 | Stromelysin-1 | M10A | C00029948 | 1 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00030117 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
C00030117
|
8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00030117
|
374 | AREG, AR, CRDGF, SDGF | amphiregulin |
C00030117
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00030117
|
664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00030117
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00030117
|
839 | CASP6, MCH2 | caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) |
C00030117
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00030117
|
1051 | CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5 | CCAAT/enhancer binding protein (C/EBP), beta |
C00030117
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00030117
|
1581 | CYP7A1, CP7A, CYP7, CYPVII | cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17) |
C00030117
|
1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00030117
|
2172 | FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP | fatty acid binding protein 6, ileal |
C00030117
|
9965 | FGF19 | fibroblast growth factor 19 |
C00030117
|
2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00030117
|
2978 | GUCA1A, C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6 | guanylate cyclase activator 1A (retina) |
C00030117
|
3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00030117
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00030117
|
3265 | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 | Harvey rat sarcoma viral oncogene homolog |
C00030117
|
3309 | HSPA5, BIP, GRP78, MIF2 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
C00030117
|
5654 | HTRA1, ARMD7, CARASIL, HtrA, L56, ORF480, PRSS11 | HtrA serine peptidase 1 (EC:3.4.21.-) |
C00030117
|
4000 | LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1 | lamin A/C |
C00030117
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00030117
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00030117
|
4671 | NAIP, BIRC1, NLRB1, psiNAIP | NLR family, apoptosis inhibitory protein |
C00030117
|
4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00030117
|
4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00030117
|
9971 | NR1H4, BAR, FXR, HRR-1, HRR1, RIP14 | nuclear receptor subfamily 1, group H, member 4 |
C00030117
|
4893 | NRAS, ALPS4, N-ras, NRAS1, NS6 | neuroblastoma RAS viral (v-ras) oncogene homolog |
C00030117
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00030117
|
23396 | PIP5K1C, LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4 | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (EC:2.7.1.68) |
C00030117
|
7001 | PRDX2, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA | peroxiredoxin 2 (EC:1.11.1.15) |
C00030117
|
10549 | PRDX4, AOE37-2, PRX-4 | peroxiredoxin 4 (EC:1.11.1.15) |
C00030117
|
5564 | PRKAB1, AMPK, HAMPKb | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
C00030117
|
5579 | PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 | protein kinase C, beta (EC:2.7.11.13) |
C00030117
|
5581 | PRKCE, PKCE, nPKC-epsilon | protein kinase C, epsilon (EC:2.7.11.13) |
C00030117
|
5590 | PRKCZ, PKC-ZETA, PKC2 | protein kinase C, zeta (EC:2.7.11.13) |
C00030117
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00030117
|
5894 | RAF1, CRAF, NS5, Raf-1, c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) |
C00030117
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00030117
|
5268 | SERPINB5, PI5, maspin | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
C00030117
|
200931 | SLC51A, OSTA, OSTalpha | solute carrier family 51, alpha subunit |
C00030117
|
123264 | SLC51B, OSTB, OSTBETA | solute carrier family 51, beta subunit |
C00030117
|
7186 | TRAF2, MGC:45012, TRAP, TRAP3 | TNF receptor-associated factor 2 |
C00030117
|
OMIM | preferred title | UniProt |
---|---|---|
#608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#613291 | Bile acid malabsorption, primary; pbam |
Q12908
|
#605479 | Cholestasis, benign recurrent intrahepatic, 2; bric2 |
O95342
|
#601847 | Cholestasis, progressive familial intrahepatic, 2; pfic2 |
O95342
|
#614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
KEGG | name | UniProt |
---|---|---|
H00624 | Familial cholestasis |
O95342
(related)
|
H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
H00966 | AICA-ribosiduria |
P31939
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H01016 | Primary bile acid malabsorption |
Q12908
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D058739 | Aberrant Crypt Foci |
C00030117
|
D001930 | Brain Injuries |
C00030117
|
D003110 | Colonic Neoplasms |
C00030117
|
D056486 | Drug-Induced Liver Injury |
C00030117
|
D005911 | Gliosis |
C00030117
|
D006965 | Hyperplasia |
C00030117
|
D008113 | Liver Neoplasms |
C00030117
|
D008114 | Liver Neoplasms, Experimental |
C00030117
|
D009069 | Movement Disorders |
C00030117
|
D009336 | Necrosis |
C00030117
|
D011230 | Precancerous Conditions |
C00030117
|
D013274 | Stomach Neoplasms |
C00030117
|