class name | count |
---|
class name | count |
---|---|
Bovidae | 3 |
Aspergillaceae | 3 |
Flavobacteriaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00030117
![]() |
Deoxycholic acid
/ 3alpha,12alpha-Dihydroxy-5.beta.-cholanoic acid |
CHEMBL348338
CHEMBL412516 CHEMBL410872 CHEMBL406393 CHEMBL1609669 CHEMBL2078862 CHEMBL2092842 CHEMBL2356050 |
D003840
|
16 / 7 / 7 | 44 / 12 |
![]() |
C00030410
![]() |
Glycocholic acid
|
CHEMBL411070
CHEMBL1354821 CHEMBL1474851 CHEMBL2074587 |
D006000
|
21 / 8 / 4 | 3 / 0 |
![]() |
C00030411
![]() |
Glycodeoxycholic acid
|
CHEMBL258605
|
D006002
|
5 / 2 / 1 | 1 / 1 |
![]() |
C00030498
![]() |
Hyodeoxycholic acid
|
CHEMBL272620
CHEMBL272621 CHEMBL1473584 CHEMBL2359483 |
C010471
|
13 / 14 / 5 | 2 / 0 |
![]() |
C00032464
![]() |
Ursodeoxycholic acid
|
CHEMBL156266
CHEMBL240597 CHEMBL1551 CHEMBL1395373 CHEMBL1439625 CHEMBL1520183 CHEMBL1981518 CHEMBL1988085 CHEMBL2074643 |
D014580
|
31 / 42 / 36 | 120 / 39 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00030117 C00030410 C00030411 C00030498 C00032464 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00030117 C00030410 C00032464 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00030117 C00030410 C00032464 | 1 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00030117 C00030410 C00032464 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00030117 C00030410 C00032464 | 1 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00030117 C00030410 C00032464 | 0 / 1 |
Q12908 | Ileal sodium/bile acid cotransporter | Bile acid | C00030117 C00030411 C00032464 | 1 / 1 |
O95342 | Bile salt export pump | drug | C00030117 C00030410 C00032464 | 2 / 1 |
Q14973 | Sodium/bile acid cotransporter | Bile acid | C00030117 C00030410 C00032464 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00030117 C00030410 C00032464 | 0 / 1 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00030117 C00030498 C00032464 | 1 / 1 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00030410 C00032464 | 0 / 0 |
P06133 | UDP-glucuronosyltransferase 2B4 | Enzyme | C00030498 C00032464 | 0 / 0 |
Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00030410 C00030411 | 1 / 0 |
Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00030410 C00030411 | 1 / 0 |
O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00030410 C00030411 | 0 / 0 |
O15439 | Multidrug resistance-associated protein 4 | Unclassified protein | C00030410 C00032464 | 0 / 0 |
P46721 | Solute carrier organic anion transporter family member 1A2 | Unclassified protein | C00030410 C00032464 | 0 / 0 |
Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00032464 | 1 / 1 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00032464 | 2 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00030410 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00030410 | 2 / 0 |
Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00030498 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00032464 | 6 / 4 |
P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00030498 | 0 / 0 |
P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00030498 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00032464 | 7 / 3 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00030117 | 0 / 0 |
P02768 | Serum albumin | Secreted protein | C00032464 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00032464 | 0 / 1 |
Q96RI1 | Bile acid receptor | NR1H4 | C00032464 | 0 / 0 |
P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00030117 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00030498 | 3 / 1 |
Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00030498 | 0 / 0 |
Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00030498 | 0 / 0 |
P37840 | Alpha-synuclein | Unclassified protein | C00032464 | 4 / 2 |
P36537 | UDP-glucuronosyltransferase 2B10 | Enzyme | C00030498 | 0 / 0 |
P23467 | Receptor-type tyrosine-protein phosphatase beta | Receptor tyrosine-protein phosphatase | C00030117 | 0 / 0 |
O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00030498 | 1 / 0 |
O75469 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 | C00032464 | 0 / 0 |
P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00030498 | 5 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00030498 | 4 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00030117 | 0 / 0 |
P08235 | Mineralocorticoid receptor | NR3C2 | C00032464 | 2 / 2 |
P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00030117 | 1 / 1 |
P04054 | Phospholipase A2 | Enzyme | C00032464 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00032464 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00032464 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00032464 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00032464 | 1 / 2 |
Q96QA9 | Multidrug resistance associated protein | Unclassified protein | C00030410 | 0 / 0 |
Q5T3U5 | Multidrug resistance-associated protein 7 | Unclassified protein | C00030410 | 0 / 0 |
Q9NYB5 | Solute carrier organic anion transporter family member 1C1 | Unclassified protein | C00030410 | 0 / 0 |
Q96J66 | ATP-binding cassette sub-family C member 11 | Unclassified protein | C00030410 | 1 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00032464 | 11 / 10 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
9971 | NR1H4, BAR, FXR, HRR-1, HRR1, RIP14 | nuclear receptor subfamily 1, group H, member 4 |
C00030117
C00030410
C00030411
C00032464
|
8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
C00030117
C00030410
C00032464
|
1051 | CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5 | CCAAT/enhancer binding protein (C/EBP), beta |
C00030117
C00032464
|
5579 | PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 | protein kinase C, beta (EC:2.7.11.13) |
C00030117
C00032464
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00030117
C00032464
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00030117
C00032464
|
5894 | RAF1, CRAF, NS5, Raf-1, c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) |
C00030117
C00032464
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00030117
C00032464
|
839 | CASP6, MCH2 | caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) |
C00030117
C00032464
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00030117
C00032464
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00030117
C00032464
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00030117
C00032464
|
1581 | CYP7A1, CP7A, CYP7, CYPVII | cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17) |
C00030117
C00032464
|
1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00030117
C00032464
|
2172 | FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP | fatty acid binding protein 6, ileal |
C00030117
C00032464
|
9965 | FGF19 | fibroblast growth factor 19 |
C00030117
C00032464
|
4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00030117
C00032464
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00030117
C00032464
|
3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00030117
C00032464
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00030117
C00032464
|
8431 | NR0B2, SHP, SHP1 | nuclear receptor subfamily 0, group B, member 2 |
C00032464
|
3309 | HSPA5, BIP, GRP78, MIF2 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
C00030117
|
5654 | HTRA1, ARMD7, CARASIL, HtrA, L56, ORF480, PRSS11 | HtrA serine peptidase 1 (EC:3.4.21.-) |
C00030117
|
4000 | LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1 | lamin A/C |
C00030117
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00030117
|
2978 | GUCA1A, C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6 | guanylate cyclase activator 1A (retina) |
C00030117
|
4671 | NAIP, BIRC1, NLRB1, psiNAIP | NLR family, apoptosis inhibitory protein |
C00030117
|
2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00030117
|
4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00030117
|
664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00030117
|
4893 | NRAS, ALPS4, N-ras, NRAS1, NS6 | neuroblastoma RAS viral (v-ras) oncogene homolog |
C00030117
|
374 | AREG, AR, CRDGF, SDGF | amphiregulin |
C00030117
|
23396 | PIP5K1C, LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4 | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (EC:2.7.1.68) |
C00030117
|
7001 | PRDX2, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA | peroxiredoxin 2 (EC:1.11.1.15) |
C00030117
|
10549 | PRDX4, AOE37-2, PRX-4 | peroxiredoxin 4 (EC:1.11.1.15) |
C00030117
|
5564 | PRKAB1, AMPK, HAMPKb | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
C00030117
|
8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00030117
|
5581 | PRKCE, PKCE, nPKC-epsilon | protein kinase C, epsilon (EC:2.7.11.13) |
C00030117
|
5590 | PRKCZ, PKC-ZETA, PKC2 | protein kinase C, zeta (EC:2.7.11.13) |
C00030117
|
7363 | UGT2B4, HLUG25, UDPGT2B4, UDPGTH1, UGT2B11 | UDP glucuronosyltransferase 2 family, polypeptide B4 (EC:2.4.1.17) |
C00030498
|
7364 | UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9 | UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17) |
C00030498
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00030117
|
5268 | SERPINB5, PI5, maspin | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
C00030117
|
200931 | SLC51A, OSTA, OSTalpha | solute carrier family 51, alpha subunit |
C00030117
|
123264 | SLC51B, OSTB, OSTBETA | solute carrier family 51, beta subunit |
C00030117
|
7186 | TRAF2, MGC:45012, TRAP, TRAP3 | TNF receptor-associated factor 2 |
C00030117
|
10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00030410
|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00032464
|
1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00032464
|
1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00032464
|
1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00032464
|
8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00032464
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00032464
|
23243 | ANKRD28, PITK, PPP1R65 | ankyrin repeat domain 28 |
C00032464
|
1173 | AP2M1, AP50, CLAPM1, mu2 | adaptor-related protein complex 2, mu 1 subunit |
C00032464
|
335 | APOA1 | apolipoprotein A-I |
C00032464
|
55937 | APOM, G3a, HSPC336, NG20, apo-M | apolipoprotein M |
C00032464
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00032464
|
644 | BLVRA, BLVR, BVR, BVRA | biliverdin reductase A (EC:1.3.1.24) |
C00032464
|
722 | C4BPA, C4BP, PRP | complement component 4 binding protein, alpha |
C00032464
|
840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00032464
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00032464
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00032464
|
6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00032464
|
595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00032464
|
896 | CCND3 | cyclin D3 |
C00032464
|
7203 | CCT3, CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5 | chaperonin containing TCP1, subunit 3 (gamma) |
C00032464
|
22948 | CCT5, CCT-epsilon, CCTE, TCP-1-epsilon | chaperonin containing TCP1, subunit 5 (epsilon) |
C00032464
|
57124 | CD248, CD164L1, TEM1 | CD248 molecule, endosialin |
C00032464
|
8837 | CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS | CASP8 and FADD-like apoptosis regulator |
C00032464
|
1267 | CNP, CNP1 | 2',3'-cyclic nucleotide 3' phosphodiesterase (EC:3.1.4.37) |
C00032464
|
1434 | CSE1L, CAS, CSE1, XPO2 | CSE1 chromosome segregation 1-like (yeast) |
C00032464
|
1464 | CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 | chondroitin sulfate proteoglycan 4 |
C00032464
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00032464
|
7818 | DAP3, DAP-3, MRP-S29, MRPS29, bMRP-10 | death associated protein 3 |
C00032464
|
1660 | DHX9, DDX9, LKP, NDH2, NDHII, RHA | DEAH (Asp-Glu-Ala-His) box helicase 9 (EC:3.6.4.13) |
C00032464
|
1737 | DLAT, DLTA, PDC-E2, PDCE2 | dihydrolipoamide S-acetyltransferase (EC:2.3.1.12) |
C00032464
|
10395 | DLC1, ARHGAP7, HP, STARD12, p122-RhoGAP | deleted in liver cancer 1 |
C00032464
|
1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00032464
|
1907 | EDN2, ET2, PPET2 | endothelin 2 |
C00032464
|
10209 | EIF1, A121, EIF-1, EIF1A, ISO1, SUI1 | eukaryotic translation initiation factor 1 |
C00032464
|
2033 | EP300, KAT3B, RSTS2, p300 | E1A binding protein p300 (EC:2.3.1.48) |
C00032464
|
79956 | ERMP1, FXNA, KIAA1815, bA207C16.3 | endoplasmic reticulum metallopeptidase 1 |
C00032464
|
8772 | FADD, MORT1 | Fas (TNFRSF6)-associated via death domain |
C00032464
|
26049 | FAM169A, SLAP75 | family with sequence similarity 169, member A |
C00032464
|
54537 | FAM35A, FAM35A1, bA163M19.1 | family with sequence similarity 35, member A |
C00032464
|
2266 | FGG | fibrinogen gamma chain |
C00032464
|
2267 | FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1 | fibrinogen-like 1 |
C00032464
|
2617 | GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1 | glycyl-tRNA synthetase (EC:6.1.1.14) |
C00032464
|
2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00032464
|
2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00032464
|
100119944 |
C00032464
|
||
2937 | GSS, GSHS | glutathione synthetase (EC:6.3.2.3) |
C00032464
|
3122 | HLA-DRA, HLA-DRA1, MLRW | major histocompatibility complex, class II, DR alpha |
C00032464
|
6927 | HNF1A, HNF-1A, HNF1, IDDM20, LFB1, MODY3, TCF-1, TCF1 | HNF1 homeobox A |
C00032464
|
6928 | HNF1B, FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1 | HNF1 homeobox B |
C00032464
|
3385 | ICAM3, CD50, CDW50, ICAM-R | intercellular adhesion molecule 3 |
C00032464
|
3458 | IFNG, IFG, IFI | interferon, gamma |
C00032464
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00032464
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00032464
|
3615 | IMPDH2, IMPD2, IMPDH-II | IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205) |
C00032464
|
3713 | IVL | involucrin |
C00032464
|
4155 | MBP | myelin basic protein |
C00032464
|
4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00032464
|
4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00032464
|
406991 | MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21 | microRNA 21 |
C00032464
|
4673 | NAP1L1, NAP1, NAP1L, NRP | nucleosome assembly protein 1-like 1 |
C00032464
|
283131 | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
C00032464
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00032464
|
3265 | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 | Harvey rat sarcoma viral oncogene homolog |
C00030117
|
8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00032464
|
220323 | OAF, NS5ATP13TP2 | OAF homolog (Drosophila) |
C00032464
|
5005 | ORM2, AGP-B, AGP-B', AGP2 | orosomucoid 2 |
C00032464
|
5580 | PRKCD, MAY1, PKCD, nPKC-delta | protein kinase C, delta (EC:2.7.10.2 2.7.11.13) |
C00032464
|
5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00032464
|
5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00032464
|
5930 | RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA | retinoblastoma binding protein 6 |
C00032464
|
117584 | RFFL, CARP-2, CARP2, FRING, RIFIFYLIN, RNF189, RNF34L | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase |
C00032464
|
387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00032464
|
22836 | RHOBTB3 | Rho-related BTB domain containing 3 |
C00032464
|
8737 | RIPK1, RIP, RIP1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 (EC:2.7.11.1) |
C00032464
|
6134 | RPL10, AUTSX5, DXS648, DXS648E, L10, NOV, QM | ribosomal protein L10 |
C00032464
|
6155 | RPL27, L27 | ribosomal protein L27 (EC:3.6.5.3) |
C00032464
|
6161 | RPL32, L32 | ribosomal protein L32 |
C00032464
|
6165 | RPL35A, DBA5, L35A | ribosomal protein L35a |
C00032464
|
116832 | RPL39L, RPL39L1 | ribosomal protein L39-like |
C00032464
|
6128 | RPL6, L6, SHUJUN-2, TAXREB107, TXREB1 | ribosomal protein L6 |
C00032464
|
6181 | RPLP2, D11S2243E, LP2, P2, RPP2 | ribosomal protein, large, P2 |
C00032464
|
6207 | RPS13, S13 | ribosomal protein S13 (EC:3.6.5.3) |
C00032464
|
51065 | RPS27L | ribosomal protein S27-like |
C00032464
|
6234 | RPS28, S28 | ribosomal protein S28 |
C00032464
|
145767 |
C00032464
|
||
55095 | SAMD4B, SMGB, hSmaug2 | sterile alpha motif domain containing 4B |
C00032464
|
23451 | SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155 | splicing factor 3b, subunit 1, 155kDa |
C00032464
|
9963 | SLC23A1, SLC23A2, SVCT1, YSPL3 | solute carrier family 23 (ascorbic acid transporter), member 1 |
C00032464
|
9962 | SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
C00032464
|
292 | SLC25A5, 2F1, AAC2, ANT2, T2, T3 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 |
C00032464
|
6522 | SLC4A2, AE2, BND3L, EPB3L1, HKB3, NBND3 | solute carrier family 4 (anion exchanger), member 2 |
C00032464
|
81848 | SPRY4, HH17 | sprouty homolog 4 (Drosophila) |
C00032464
|
6742 | SSBP1, Mt-SSB, SOSS-B1, SSBP, mtSSB | single-stranded DNA binding protein 1, mitochondrial |
C00032464
|
6772 | STAT1, CANDF7, ISGF-3, STAT91 | signal transducer and activator of transcription 1, 91kDa |
C00032464
|
6788 | STK3, KRS1, MST2 | serine/threonine kinase 3 (EC:2.7.11.1) |
C00032464
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00032464
|
7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00032464
|
8795 | TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | tumor necrosis factor receptor superfamily, member 10b |
C00032464
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00032464
|
55339 | WDR33, NET14, WDC146 | WD repeat domain 33 |
C00032464
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#117800 | Apocrine gland secretion, variation in |
Q96J66
|
#613291 | Bile acid malabsorption, primary; pbam |
Q12908
|
#601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
#612560 | Bone mineral density quantitative trait locus 12; bmnd12 |
O75795
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#605479 | Cholestasis, benign recurrent intrahepatic, 2; bric2 |
O95342
|
#601847 | Cholestasis, progressive familial intrahepatic, 2; pfic2 |
O95342
|
#114500 | Colorectal cancer; crc |
P84022
|
#218800 | Crigler-najjar syndrome, type i |
P22309
|
#606785 | Crigler-najjar syndrome, type ii |
P22309
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#237500 | Dubin-johnson syndrome; djs |
Q92887
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#143500 | Gilbert syndrome |
P22309
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
#237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#605115 | Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy |
P08235
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#177735 | Pseudohypoaldosteronism, type i, autosomal dominant; pha1a |
P08235
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00624 | Familial cholestasis |
O95342
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00243 | Hyperkalemic distal renal tubular acidosis (RTA type 4) |
P08235
(related)
|
H00603 | Hypertension exacerbated in pregnancy |
P08235
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
H00966 | AICA-ribosiduria |
P31939
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H01016 | Primary bile acid malabsorption |
Q12908
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D058739 | Aberrant Crypt Foci |
C00030117
C00032464 |
D010195 | Pancreatitis |
C00030411
C00032464 |
D003110 | Colonic Neoplasms |
C00030117
C00032464 |
D056486 | Drug-Induced Liver Injury |
C00030117
C00032464 |
D009336 | Necrosis |
C00030117
C00032464 |
D005234 | Fatty Liver |
C00032464
|
D008113 | Liver Neoplasms |
C00030117
|
D008114 | Liver Neoplasms, Experimental |
C00030117
|
D009069 | Movement Disorders |
C00030117
|
D005911 | Gliosis |
C00030117
|
D011230 | Precancerous Conditions |
C00030117
|
D013274 | Stomach Neoplasms |
C00030117
|
D001930 | Brain Injuries |
C00030117
|
D001649 | Bile Duct Diseases |
C00032464
|
D002761 | Cholangitis |
C00032464
|
D015209 | Cholangitis, Sclerosing |
C00032464
|
D002769 | Cholelithiasis |
C00032464
|
D002779 | Cholestasis |
C00032464
|
D002780 | Cholestasis, Intrahepatic |
C00032464
|
C535932 | Cholestasis, intrahepatic of pregnancy |
C00032464
|
C535933 | Cholestasis, progressive familial intrahepatic 1 |
C00032464
|
D003550 | Cystic Fibrosis |
C00032464
|
D005221 | Fatigue |
C00032464
|
D006965 | Hyperplasia |
C00030117
|
D005355 | Fibrosis |
C00032464
|
D005705 | Gallbladder Diseases |
C00032464
|
D042882 | Gallstones |
C00032464
|
D019698 | Hepatitis C, Chronic |
C00032464
|
D006521 | Hepatitis, Chronic |
C00032464
|
D006943 | Hyperglycemia |
C00032464
|
D006980 | Hyperthyroidism |
C00032464
|
D007037 | Hypothyroidism |
C00032464
|
D007249 | Inflammation |
C00032464
|
D007333 | Insulin Resistance |
C00032464
|
D007565 | Jaundice |
C00032464
|
D041781 | Jaundice, Obstructive |
C00032464
|
D008103 | Liver Cirrhosis |
C00032464
|
D008105 | Liver Cirrhosis, Biliary |
C00032464
|
D008106 | Liver Cirrhosis, Experimental |
C00032464
|
D008107 | Liver Diseases |
C00032464
|
D017114 | Liver Failure, Acute |
C00032464
|
D009078 | Mucocele |
C00032464
|
D009369 | Neoplasms |
C00032464
|
D017094 | Porphyrias, Hepatic |
C00032464
|
D011183 | Postoperative Complications |
C00032464
|
D011537 | Pruritus |
C00032464
|
D015431 | Weight Loss |
C00032464
|