Ephedra equisetina Bge.
Species
KNApSAcK Entry
| Organism name | Ephedra equisetina Bge. |
|---|---|
| Genus | Ephedra |
| Family | Ephedraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ephedra |
|---|---|
| Linked NCBI taxonomy ID | 3387 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Ephedraceae |
|---|---|
| ID | 3386 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00031097
|
Pseudoephedrine
/ trans-Ephedrine / (+)-Pseudoephedrine |
CHEMBL357080
CHEMBL211456 CHEMBL1590 CHEMBL1620154 CHEMBL2110656 CHEMBL2110905 |
D054199
|
13 / 12 / 10 | 0 / 50 | No. 2149 | No. 9 |
|
Human Protein / Gene in interactions
13 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00031097 | 1 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00031097 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00031097 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00031097 | 0 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00031097 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00031097 | 1 / 1 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00031097 | 2 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00031097 | 3 / 3 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00031097 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00031097 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00031097 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00031097 | 0 / 1 |
| P40225 | Thrombopoietin | Unclassified protein | C00031097 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P18054
|
| #301500 | Fabry disease |
P06280
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
Diseases related to CTD interactions
50 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D054058 | Acute Coronary Syndrome |
C00031097
|
| D058186 | Acute Kidney Injury |
C00031097
|
| D000787 | Angina Pectoris |
C00031097
|
| D000799 | Angioedema |
C00031097
|
| D001146 | Arrhythmia, Sinus |
C00031097
|
| D001259 | Ataxia |
C00031097
|
| D001714 | Bipolar Disorder |
C00031097
|
| D001929 | Brain Edema |
C00031097
|
| D009202 | Cardiomyopathies |
C00031097
|
| D002543 | Cerebral Hemorrhage |
C00031097
|
| D017091 | Colitis, Ischemic |
C00031097
|
| D003139 | Common Cold |
C00031097
|
| D003329 | Coronary Vasospasm |
C00031097
|
| D003873 | Dermatitis, Exfoliative |
C00031097
|
| D006970 | Disorders of Excessive Somnolence |
C00031097
|
| D004244 | Dizziness |
C00031097
|
| D004342 | Drug Hypersensitivity |
C00031097
|
| D062787 | Drug Overdose |
C00031097
|
| D006261 | Headache |
C00031097
|
| D006333 | Heart Failure |
C00031097
|
| D006967 | Hypersensitivity |
C00031097
|
| D006973 | Hypertension |
C00031097
|
| D020343 | Hypertensive Encephalopathy |
C00031097
|
| D007251 | Influenza, Human |
C00031097
|
| D053609 | Lethargy |
C00031097
|
| D009203 | Myocardial Infarction |
C00031097
|
| D009207 | Myoclonus |
C00031097
|
| D009668 | Nose Diseases |
C00031097
|
| D010554 | Personality Disorders |
C00031097
|
| D010612 | Pharyngitis |
C00031097
|
| D011605 | Psychoses, Substance-Induced |
C00031097
|
| D011644 | Puerperal Disorders |
C00031097
|
| D012220 | Rhinitis |
C00031097
|
| D012221 | Rhinitis, Allergic, Perennial |
C00031097
|
| D006255 | Rhinitis, Allergic, Seasonal |
C00031097
|
| D012640 | Seizures |
C00031097
|
| D012852 | Sinusitis |
C00031097
|
| D020521 | Stroke |
C00031097
|
| D013575 | Syncope |
C00031097
|
| D013614 | Tachycardia, Paroxysmal |
C00031097
|
| D013617 | Tachycardia, Supraventricular |
C00031097
|
| D017180 | Tachycardia, Ventricular |
C00031097
|
| D014202 | Tremor |
C00031097
|
| D014545 | Urinary Calculi |
C00031097
|
| D016055 | Urinary Retention |
C00031097
|
| D052878 | Urolithiasis |
C00031097
|
| D014581 | Urticaria |
C00031097
|
| D018879 | Ventricular Premature Complexes |
C00031097
|
| D014839 | Vomiting |
C00031097
|
| D014987 | Xerostomia |
C00031097
|