| Organism name | Salvia pachyphylla |
|---|---|
| Genus | Salvia |
| Family | Labiatae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Salvia pachyphylla |
|---|---|
| Linked NCBI taxonomy ID | 207759 |
| Linked level | species |
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00036880
|
Carnosic acid
|
CHEMBL484853
CHEMBL1397655 |
C018381
|
17 / 23 / 55 | 6 / 4 | No. 323 | No. 41 |
|
|
C00031191
|
Rosmanol
|
No. 734 | No. 40 |
|
||||
|
C00041292
|
7-Methoxyrosmanol
/ (+)-7-Methoxyrosmanol |
CHEMBL464376
CHEMBL1081338 |
No. 734 | No. 40 |
|
|||
|
C00037344
|
Isorosmanol
|
CHEMBL494659
CHEMBL2333536 |
No. 734 | No. 40 |
|
|||
|
C00041281
|
5,6-Didehydro-O-methylsugiol
|
CHEMBL494660
|
No. 1418 |
|
||||
|
C00041258
|
20-Deoxocarnosol
|
CHEMBL491879
|
No. 2253 |
|
||||
|
C00041232
|
11,12-Dioxoabieta-8,13-diene
/ (-)-11,12-Dioxoabieta-8,13-diene |
No. 2951 |
|
|||||
|
C00041294
|
8beta-Hydroxy-9(11),13-abietadien-12-one
/ (-)-8beta-Hydroxy-9(11),13-abietadien-12-one |
CHEMBL243549
|
No. 5158 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00036880 | 7 / 37 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00036880 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00036880 | 2 / 3 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00036880 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00036880 | 0 / 0 |
| P16233 | Pancreatic triacylglycerol lipase | Hydrolase | C00036880 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00036880 | 2 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00036880 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00036880 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00036880 | 2 / 2 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00036880 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00036880 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00036880 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00036880 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00036880 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00036880 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00036880 | 1 / 2 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 100136148 |
C00036880
|
||
| 929 | CD14 | CD14 molecule |
C00036880
|
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00036880
|
| 5914 | RARA, NR1B1, RAR | retinoic acid receptor, alpha |
C00036880
|
| 6256 | RXRA, NR2B1 | retinoid X receptor, alpha |
C00036880
|
| 7421 | VDR, NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor |
C00036880
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|