Species

KNApSAcK Entry

Organism name Roldana barba-johannis
Genus Roldana
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Roldana barba-johannis
Linked NCBI taxonomy ID 344068
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00031302 External link 512 Sargaquinoic acid
No. 661
C00031300 External link 512 Sargachromenol
CHEMBL1668777
CHEMBL1668778
7 / 7 / 10 No. 2359
C00031301 External link 512 Sargahydroquinoic acid
CHEMBL261063
No. 3586

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10276 Retinoic acid receptor alpha NR1B1 C00031300 1 / 2
P04150 Glucocorticoid receptor NR3C1 C00031300 0 / 1
P06401 Progesterone receptor NR3C3 C00031300 0 / 1
Q96RI1 Bile acid receptor NR1H4 C00031300 0 / 0
P03372 Estrogen receptor NR3A1 C00031300 1 / 1
P08235 Mineralocorticoid receptor NR3C2 C00031300 2 / 2
P10275 Androgen receptor NR3C4 C00031300 3 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#612376 Acute promyelocytic leukemia; apl P10276
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#615363 Estrogen resistance; estrr P03372
#605115 Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy P08235
#177735 Pseudohypoaldosteronism, type i, autosomal dominant; pha1a P08235
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (10)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
P06401 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00243 Hyperkalemic distal renal tubular acidosis (RTA type 4) P08235 (related)
H00603 Hypertension exacerbated in pregnancy P08235 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00003 Acute myeloid leukemia (AML) P10276 (related)
P10276 (marker)
H00516 Isolated orofacial clefts P10276 (related)