Pinus grandis
Species
KNApSAcK Entry
| Organism name | Pinus grandis |
|---|---|
| Genus | Pinus |
| Family | Pinaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Pinaceae |
|---|---|
| Linked NCBI taxonomy ID | 3318 |
| Linked level | family |
Family
| Family in NCBI taxonomy | Pinaceae |
|---|---|
| ID | 3318 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000868
|
Abieta-7,13-diene
|
No. 1536 | No. 40 |
|
||||
|
C00000869
|
Abietal
/ 7,13-Abietadien-18-al / Abieta-7,13-diene-18-al |
CHEMBL563793
|
No. 1536 | No. 40 |
|
|||
|
C00000870
|
Abietol
/ Abietinol / Abieta-7,13-diene-18-ol |
CHEMBL304954
CHEMBL1436063 |
C026490
|
9 / 12 / 10 | No. 1536 | No. 40 |
|
|
|
C00000871
|
Abietic acid
/ 7,13-Abietadien-18-oic acid |
CHEMBL71893
CHEMBL1336124 CHEMBL1357151 CHEMBL1514489 CHEMBL1552001 |
C023710
|
18 / 22 / 25 | No. 1536 | No. 40 |
|
Human Protein / Gene in interactions
19 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P02545 | Prelamin-A/C | Unclassified protein | C00000870 C00000871 | 11 / 10 |
| Q15120 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial | Pdhk | C00000870 C00000871 | 1 / 0 |
| Q15119 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial | Pdhk | C00000870 C00000871 | 0 / 0 |
| Q16654 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial | Pdhk | C00000870 C00000871 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000870 C00000871 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000870 C00000871 | 0 / 0 |
| Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial | Pdhk | C00000870 C00000871 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000870 C00000871 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000871 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000871 | 3 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000871 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000871 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000871 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000871 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000870 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000871 | 2 / 3 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000871 | 0 / 1 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000871 | 0 / 3 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000871 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (22)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #300905 | Charcot-marie-tooth disease, x-linked dominant, 6; cmtx6 |
Q15120
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (25)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|