PCIDB

KNApSAcK Metabolite C00000870

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00000870
Name	Abietol / Abietinol / Abieta-7,13-diene-18-ol
CAS RN	666-84-2
Standard InChI	InChI=1S/C20H32O/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h7,12,14,17-18,21H,5-6,8-11,13H2,1-4H3/t17-,18-,19-,20+/m0/s1
Standard InChI (Main Layer)	InChI=1S/C20H32O/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h7,12,14,17-18,21H,5-6,8-11,13H2,1-4H3

Cluster

Phytochemical cluster	No. 40
KCF-S cluster	No. 1536

Link

ChEMBL

By standard InChI	CHEMBL304954
By standard InChI Main Layer	CHEMBL304954 CHEMBL1436063

KEGG

By LinkDB	C11882

CTD

By CAS RN	C026490

Species

Summary

Plant class

class name	count
Spermatophyta	4

Family

family name	count
Pinaceae	2
Cupressaceae	2

List (4)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Juniperus phoenicea	61308	Cupressaceae	Spermatophyta	Viridiplantae
Juniperus thurifera var.africana	13100	Cupressaceae	Spermatophyta	Viridiplantae
Pinus contorta	3339	Pinaceae	Spermatophyta	Viridiplantae
Pinus grandis	3318	Pinaceae	Spermatophyta	Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P02545	Prelamin-A/C	Unclassified protein	CHEMBL1436063	CHEMBL1614544 (1)	11 / 10
P00352	Retinal dehydrogenase 1	Enzyme	CHEMBL1436063	CHEMBL1614458 (1)	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	CHEMBL1436063	CHEMBL1794467 (1)	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	CHEMBL1436063	CHEMBL1614521 (1)	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	CHEMBL1436063	CHEMBL1614240 (1)	0 / 0
Q15118	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	Pdhk	CHEMBL304954	CHEMBL764813 (1)	0 / 0
Q16654	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial	Pdhk	CHEMBL304954	CHEMBL764813 (1)	0 / 0
Q15119	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial	Pdhk	CHEMBL304954	CHEMBL764813 (1)	0 / 0
Q15120	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial	Pdhk	CHEMBL304954	CHEMBL764813 (1)	1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM	preferred title	UniProt
#115200	Cardiomyopathy, dilated, 1a; cmd1a	P02545
#212112	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	P02545
#605588	Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1	P02545
#300905	Charcot-marie-tooth disease, x-linked dominant, 6; cmtx6	Q15120
#181350	Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2	P02545
#610140	Heart-hand syndrome, slovenian type	P02545
#176670	Hutchinson-gilford progeria syndrome; hgps	P02545
#151660	Lipodystrophy, familial partial, type 2; fpld2	P02545
#248370	Mandibuloacral dysplasia with type a lipodystrophy; mada	P02545
#613205	Muscular dystrophy, congenital, lmna-related	P02545
#159001	Muscular dystrophy, limb-girdle, type 1b; lgmd1b	P02545
#275210	Restrictive dermopathy, lethal	P02545

KEGG DISEASE (10)

KEGG	disease name	UniProt
H00264	Charcot-Marie-Tooth disease (CMT)	P02545 (related)
H00294	Dilated cardiomyopathy (DCM)	P02545 (related)
H00420	Familial partial lipodystrophy (FPL)	P02545 (related)
H00563	Emery-Dreifuss muscular dystrophy	P02545 (related)
H00590	Congenital muscular dystrophies (CMD/MDC)	P02545 (related)
H00593	Limb-girdle muscular dystrophy (LGMD)	P02545 (related)
H00601	Hutchinson-Gilford progeria syndrome	P02545 (related)
H00663	Restrictive dermopathy	P02545 (related)
H00665	Mandibuloacral dysplasia	P02545 (related)
H01216	Left ventricular noncompaction (LVNC)	P02545 (related)