Species

KNApSAcK Entry

Organism name Phaeosphaeria sp. L487
Genus Phaeosphaeria
Family Phaeosphaeriaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Phaeosphaeria sp. L487
Linked NCBI taxonomy ID 65784
Linked level species

Family

Family in NCBI taxonomy Phaeosphaeriaceae
ID 5020

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000908 External link 512 GGPP
/ Geranylgeranyl diphosphate
/ Geranylgeranyl pyrophosphate
CHEMBL1160059
CHEMBL1160061
CHEMBL1229266
C002963
3 / 0 / 0 34 / 0 No. 4178 No. 38
C00000880 External link 512 ent-CPP
/ ent-Copalyl diphosphate
No. 4186 No. 46

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P49356 Protein farnesyltransferase subunit beta Enzyme C00000908 0 / 0
P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Enzyme C00000908 0 / 0
P53609 Geranylgeranyl transferase type-1 subunit beta Enzyme C00000908 0 / 0

34 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000908
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000908
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00000908
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000908
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00000908
1277 COL1A1, OI4 collagen, type I, alpha 1 C00000908
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00000908
1490 CTGF, CCN2, HCS24, IGFBP8, NOV2 connective tissue growth factor C00000908
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00000908
9453 GGPS1, GGPPS, GGPPS1 geranylgeranyl diphosphate synthase 1 (EC:2.5.1.1 2.5.1.10 2.5.1.29) C00000908
3156 HMGCR, LDLCQ3 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) C00000908
3265 HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 Harvey rat sarcoma viral oncogene homolog C00000908
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000908
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00000908
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000908
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00000908
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000908
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000908
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000908
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00000908
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00000908
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00000908
8013 NR4A3, CHN, CSMF, MINOR, NOR1, TEC nuclear receptor subfamily 4, group A, member 3 C00000908
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00000908
5155 PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis platelet-derived growth factor beta polypeptide C00000908
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000908
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00000908
56729 RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1 resistin C00000908
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00000908
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00000908
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00000908
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000908
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00000908
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00000908