Menegazzia terebrata
Species
KNApSAcK Entry
| Organism name | Menegazzia terebrata |
|---|---|
| Genus | |
| Family | |
| Kingdom |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Menegazzia terebrata |
|---|---|
| Linked NCBI taxonomy ID | 180482 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Parmeliaceae |
|---|---|
| ID | 78060 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00040391
|
Stictic acid
|
CHEMBL173530
|
30 / 22 / 24 | No. 3496 |
|
|||
|
C00036782
|
Parmelin
/ Atranorin / Usnarin acid |
CHEMBL173395
|
C026304
|
2 / 0 / 1 | 5 / 3 | No. 3861 |
|
|
|
C00047798
|
Chloroatranorin
|
No. 3861 |
|
Human Protein / Gene in interactions
31 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00036782 C00040391 | 0 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00036782 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00040391 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00040391 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00040391 | 3 / 1 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00040391 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00040391 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00040391 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00040391 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00040391 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00040391 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00040391 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00040391 | 1 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00040391 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00040391 | 2 / 2 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00040391 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00040391 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00040391 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00040391 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00040391 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00040391 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00040391 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00040391 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00040391 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00040391 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00040391 | 2 / 5 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00040391 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00040391 | 1 / 4 |
| P63165 | Small ubiquitin-related modifier 1 | Unclassified protein | C00040391 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00040391 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00040391 | 2 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00036782
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00036782
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00036782
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00036782
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00036782
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (22)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #613705 | Orofacial cleft 10; ofc10 |
P63165
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (24)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00516 | Isolated orofacial clefts |
P63165
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|