Luffariella sp.
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00046094
|
Luffariolide H
/ (+)-Luffariolide H |
No. 9 | No. 51 |
|
||||
|
C00039662
|
Luffolide
|
C059349
|
No. 691 |
|
||||
|
C00039661
|
Luffariellolide
|
CHEMBL451037
|
C076150
|
1 / 0 / 0 | No. 1329 |
|
||
|
C00039732
|
Manoalide
|
CHEMBL463914
CHEMBL497528 |
C045673
|
4 / 0 / 0 | 3 / 1 | No. 1694 |
|
|
|
C00050148
|
Luffasterol B
/ (-)-Luffasterol B |
No. 3802 |
|
|||||
|
C00050147
|
Luffasterol A
/ (-)-Luffasterol A |
No. 3802 |
|
|||||
|
C00050149
|
Luffasterol C
/ (-)-Luffasterol C |
No. 3802 |
|
|||||
|
C00046095
|
Luffariolide J
|
No. 3971 |
|
Human Protein / Gene in interactions
4 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P14555 | Phospholipase A2, membrane associated | Enzyme | C00039661 C00039732 | 0 / 0 |
| P04054 | Phospholipase A2 | Enzyme | C00039732 | 0 / 0 |
| Q9UNK4 | Group IID secretory phospholipase A2 | Enzyme | C00039732 | 0 / 0 |
| Q9H2U1 | Probable ATP-dependent RNA helicase DHX36 | Enzyme | C00039732 | 0 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00039732
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00039732
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00039732
|