PCIDB

Cuscuta spp.

Species

KNApSAcK Entry

Organism name Cuscuta spp.
Genus Cuscuta
Family Convolvulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cuscuta
Linked NCBI taxonomy ID 4128
Linked level genus

Family

Family in NCBI taxonomy Convolvulaceae
ID 4118

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00000926 External link 512 gamma-Carotene
No. 131 No. 59
C00001677 External link 512 Agroclavine
CHEMBL449081
CHEMBL481772
CHEMBL1999620
C004465
19 / 13 / 16 No. 987 No. 4

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001677 1 / 0
Q99700 Ataxin-2 Unclassified protein C00001677 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001677 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001677 1 / 0
P11473 Vitamin D3 receptor NR1I1 C00001677 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00001677 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001677 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001677 1 / 2
Q99816 Tumor susceptibility gene 101 protein Unclassified protein C00001677 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001677 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001677 4 / 3
P06239 Tyrosine-protein kinase Lck Src C00001677 0 / 1
P43405 Tyrosine-protein kinase SYK Syk C00001677 0 / 0
P51451 Tyrosine-protein kinase Blk Src C00001677 1 / 1
Q14145 Kelch-like ECH-associated protein 1 Unclassified protein C00001677 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001677 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00001677 0 / 0
O00255 Menin Unclassified protein C00001677 2 / 5
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001677 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613375 Maturity-onset diabetes of the young, type 11; mody11 P51451
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00410 Maturity onset diabetes of the young (MODY) P51451 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)