PCIDB

Diospyros lycioides

Family in NCBI taxonomy	Ebenaceae
ID	19955

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	asterids
ID	71274

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00043693	Mamegakinone					No. 312
C00043720	Methylnaphthazarin	CHEMBL11475		20 / 15 / 15		No. 1047	No. 80

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00043720	0 / 0
P06746	DNA polymerase beta	Enzyme	C00043720	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00043720	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00043720	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00043720	3 / 1
P54132	Bloom syndrome protein	Enzyme	C00043720	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00043720	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00043720	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00043720	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00043720	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00043720	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00043720	1 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00043720	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00043720	1 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00043720	1 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00043720	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00043720	4 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00043720	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00043720	0 / 0
O00255	Menin	Unclassified protein	C00043720	2 / 5

OMIM	preferred title	UniProt
#608584	Asthma-related traits, susceptibility to, 2	Q6W5P4
#210900	Bloom syndrome; blm	P54132
#600274	Frontotemporal dementia; ftd	P10636
#232300	Glycogen storage disease ii	P10253
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#145000	Hyperparathyroidism 1; hrpt1	O00255
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#160900	Myotonic dystrophy 1; dm1	Q9NR56
#257220	Niemann-pick disease, type c1; npc1	O15118
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636
#188570	Thyroid hormone resistance, generalized, autosomal dominant; grth	P10828
#274300	Thyroid hormone resistance, generalized, autosomal recessive; grth	P10828
#145650	Thyroid hormone resistance, selective pituitary; prth	P10828

KEGG	name	UniProt
H00033	Adrenal carcinoma	O00255 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00136	Niemann-Pick disease type C (NPC)	O15118 (related)
H00069	Glycogen storage diseases (GSD)	P10253 (related)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H00249	Thyroid hormone resistance syndrome	P10828 (related)
H00094	DNA repair defects	P54132 (related)
H00296	Defects in RecQ helicases	P54132 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q03164 (related) Q03164 (marker)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)