| Organism name | Machaerium villosum |
|---|---|
| Genus | Machaerium |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Machaerium villosum |
|---|---|
| Linked NCBI taxonomy ID | 450039 |
| Linked level | species |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00009390
|
3'-Methoxydaidzein
|
CHEMBL450602
|
No. 3 | No. 15 |
|
|||
|
C00009382
|
Isoformononetin
|
CHEMBL453280
|
1 / 1 / 1 | No. 3 | No. 15 |
|
||
|
C00009389
|
Cyclosin
/ Calycosin / 3'-Hydroxyformononetin |
CHEMBL241608
|
10 / 9 / 6 | No. 3 | No. 15 |
|
||
|
C00000945
|
Butin
/ 7,3',4'-Trihydroxyflavanone |
CHEMBL451168
|
C051437
|
No. 25 | No. 14 |
|
||
|
C00009384
|
3'-Hydroxydaidzein
/ 7,3',4'-Trihydroxyisoflavone |
CHEMBL13486
|
C061213
|
4 / 7 / 4 | 8 / 0 | No. 71 | No. 15 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06746 | DNA polymerase beta | Enzyme | C00009389 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00009384 | 1 / 1 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00009384 | 0 / 0 |
| P14174 | Macrophage migration inhibitory factor | Enzyme | C00009384 | 1 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00009389 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00009389 | 4 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00009384 | 5 / 3 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00009389 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00009389 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00009382 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00009389 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00009389 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00009389 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00009389 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00009389 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00009384
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00009384
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00009384
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00009384
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00009384
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00009384
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00009384
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00009384
|
| OMIM | preferred title | UniProt |
|---|---|---|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #604302 | Rheumatoid arthritis, systemic juvenile |
P14174
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278300 | Xanthinuria, type i |
P47989
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|