Erythrina fusca
Species
KNApSAcK Entry
| Organism name | Erythrina fusca |
|---|---|
| Genus | Erythrina |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Erythrina fusca |
|---|---|
| Linked NCBI taxonomy ID | 556509 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (17)
| Species | Activity |
|---|---|
| Erythrina fusca Lour. | Analgesic |
| Erythrina fusca Lour. | Analgesic |
| Erythrina fusca Lour. | Antipyretic |
| Erythrina fusca Lour. | Antiseptic |
| Erythrina fusca Lour. | Antiseptic |
| Erythrina fusca Lour. | Antitussive |
| Erythrina fusca Lour. | Antitussive |
| Erythrina fusca Lour. | Diaphoretic |
| Erythrina fusca Lour. | Febrifuge |
| Erythrina fusca Lour. | Hallucinogen |
| Erythrina fusca Lour. | Hallucinogenic |
| Erythrina fusca Lour. | Narcotic |
| Erythrina fusca Lour. | Narcotic |
| Erythrina fusca Lour. | Purgative |
| Erythrina fusca Lour. | Sudorific |
| Erythrina fusca Lour. | Vermifuge |
| Erythrina fusca Lour. | Vermifuge |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00019155
|
8-Prenyldaidzein
|
No. 15 | No. 15 |
|
||||
|
C00000954
|
Senegalensein
/ Lonchocarpol A / 6,8-Diprenylnaringenin |
CHEMBL477969
CHEMBL1545584 |
C068505
|
16 / 26 / 18 | No. 19 | No. 14 |
|
|
|
C00000977
|
Liquiritigenin
|
CHEMBL252642
CHEMBL271939 |
C083152
|
5 / 4 / 4 | 1 / 1 | No. 25 | No. 14 |
|
|
C00008249
|
Cajaflavanone
/ Erythrisenegalone |
CHEMBL557692
|
No. 39 |
|
||||
|
C00008262
|
Lupinifolin
|
CHEMBL559980
|
No. 39 |
|
||||
|
C00008450
|
Citflavanone
|
No. 127 | No. 14 |
|
||||
|
C00019388
|
3-Hydroxy-9-methoxy-10-(3-hydroxy-3-methylbutyl)pterocarpan
|
No. 188 | No. 15 |
|
||||
|
C00009687
|
Sandwicarpin
/ 6a-Hydroxyphaseollidin |
No. 325 | No. 15 |
|
||||
|
C00002515
|
Cristacarpin
/ Erythrabyssin I |
CHEMBL454849
|
C085157
|
2 / 1 / 1 | No. 325 | No. 15 |
|
Human Protein / Gene in interactions
23 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000977 | 0 / 0 |
| P17861 | X-box-binding protein 1 | Unclassified protein | C00000954 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000954 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000954 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00000954 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00000954 | 6 / 4 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000977 | 2 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000954 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000954 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00000954 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002515 | 0 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000954 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000954 | 7 / 3 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00000977 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000977 | 2 / 2 |
| P03372 | Estrogen receptor | NR3A1 | C00002515 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000954 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000954 | 4 / 3 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00000977 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000954 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00000954 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000954 | 1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000954 | 1 / 1 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1831 | TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP | TSC22 domain family, member 3 |
C00000977
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (31)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (23)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00025 | Penile cancer |
P14780
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|