PCIDB

Lespedeza spp.

Species

KNApSAcK Entry

Organism name Lespedeza spp.
Genus Lespedeza
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lespedeza
Linked NCBI taxonomy ID 53892
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00001110 External link 512 Vitexin
/ Apigenin 8-C-glucoside
/ 8-D-Glucosyl-4',5,7-trihydroxyflavone
/ 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL487417
CHEMBL1332209
CHEMBL1357921
16 / 4 / 8 No. 22 No. 15
C00000969 External link 512 Homoeriodictyol
CHEMBL398282
CHEMBL490170
4 / 4 / 4 No. 25 No. 14

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000969 C00001110 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000969 4 / 4
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001110 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000969 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001110 0 / 1
O75496 Geminin Unclassified protein C00001110 0 / 0
P15121 Aldose reductase Enzyme C00001110 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001110 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001110 0 / 0
P06746 DNA polymerase beta Enzyme C00000969 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001110 1 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001110 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001110 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001110 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001110 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001110 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001110 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001110 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001110 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#604229 Peters anomaly Q16678
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)