Esenbeckia yaxhoob Lundell

• Index
• Plant Species
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Esenbeckia yaxhoob Lundell
Genus	Esenbeckia
Family	Rutaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rutaceae
Linked NCBI taxonomy ID	23513
Linked level	family

Family

Family in NCBI taxonomy	Rutaceae
ID	23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00000970	Hesperidin	CHEMBL265606 CHEMBL449317 CHEMBL1314714 CHEMBL1328143 CHEMBL1535112 CHEMBL1574000 CHEMBL2140112	D006569	24 / 9 / 14	10 / 5	No. 48	No. 14
C00002477	Imperatorin	CHEMBL453805	C031534	18 / 7 / 6	1 / 1	No. 606	No. 25
C00035530	Asarinin		C006637			No. 621	No. 21
C00036263	2-Tridecanone	CHEMBL480097	C009541			No. 1611

Human Protein / Gene in interactions

41 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P83916	Chromobox protein homolog 1	Unclassified protein	C00000970 C00002477	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000970 C00002477	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00000970 C00002477	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000970 C00002477	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002477	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000970	0 / 0
P62158	Calmodulin	Unclassified protein	C00000970	1 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003749	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002477	0 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00002477	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000970	0 / 1
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00000970	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002477	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00002477	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002477	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000970	1 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00000970	1 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000970	1 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002477	1 / 1
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00002477	0 / 0
P56817	Beta-secretase 1	A1A	C00002477	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000970	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000970	1 / 1
P06746	DNA polymerase beta	Enzyme	C00000970	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000970	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002477	2 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000970	0 / 0
Q9Y251	Heparanase	Enzyme	C00000970	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000970	0 / 0
O00167	Eyes absent homolog 2	Enzyme	C00002477	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002477	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000970	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002477	1 / 0
O00255	Menin	Unclassified protein	C00000970	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000970	1 / 2
Q02410	Amyloid beta A4 precursor protein-binding family A member 1	Unclassified protein	C00000970	0 / 0
Q00975	Voltage-dependent N-type calcium channel subunit alpha-1B	N-TYPE	C00000970	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000970	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002477	1 / 1

13 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002477
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000970
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000970
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00000970
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000970
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000970
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00000970
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00000970
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000970
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000970
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000970

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions