Species

KNApSAcK Entry

Organism name Melilotus polonicus
Genus Melilotus
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Melilotus
Linked NCBI taxonomy ID 47081
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000977 External link 512 Liquiritigenin
CHEMBL252642
CHEMBL271939
C083152
5 / 4 / 4 1 / 1 No. 25 No. 14
C00002547 External link 512 (-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan
CHEMBL238845
CHEMBL413297
C047353
3 / 1 / 1 No. 66 No. 15

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000977 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000977 2 / 2
O75496 Geminin Unclassified protein C00002547 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00000977 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00000977 2 / 2
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002547 0 / 0
P05412 Transcription factor AP-1 Transcription Factor C00000977 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002547 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1831 TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP TSC22 domain family, member 3 C00000977

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780

KEGG DISEASE (5)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00025 Penile cancer P14780 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009120 Muscle Cramp C00000977