Species

KNApSAcK Entry

Organism name Cynara scolymus
Genus Cynara
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cynara cardunculus var. scolymus
Linked NCBI taxonomy ID 59895
Linked level varietas

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006658 External link 512 Cyanidin 3-sophoroside
No. 1 No. 15
C00004304 External link 512 Luteolin 7-rutinoside-4'-glucoside
No. 5 No. 15
C00000984 External link 512 Narirutin
CHEMBL446246
CHEMBL507672
CHEMBL1441712
No. 48 No. 14
C00020513 External link 512 Dehydrocyanaropicrin
No. 206 No. 38
C00003243 External link 512 Cynaropicrin
CHEMBL374146
C075687
1 / 0 / 0 No. 206 No. 38
C00002733 External link 512 1,3-Dicaffeoylquinic acid
CHEMBL431948
CHEMBL487258
CHEMBL478574
CHEMBL1213299
CHEMBL2105478
CHEMBL2356300
6 / 5 / 7 No. 518 No. 6
C00020538 External link 512 Isoamberboin
No. 608
C00020855 External link 512 Cynaratriol
No. 608
C00003297 External link 512 Grosshemin
CHEMBL271958
CHEMBL1968792
C007887
6 / 2 / 1 No. 2173 No. 38

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00003297 1 / 1
O75496 Geminin Unclassified protein C00003297 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002733 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003297 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00003243 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002733 0 / 0
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002733 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003297 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00002733 0 / 1
P24298 Alanine aminotransferase 1 Enzyme C00002733 0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002733 3 / 3
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003297 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00003297 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#209950 Atypical mycobacteriosis, familial P42224
#614162 Candidiasis, familial, 7; candf7 P42224
#137800 Glioma susceptibility 1; glm1 O75874
#245590 Growth hormone insensitivity with immunodeficiency P51692
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (8)

KEGG name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)