Species

KNApSAcK Entry

Organism name Cedrela odorata
Genus Cedrela
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cedrela odorata
Linked NCBI taxonomy ID 124947
Linked level species

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (14)

Species Activity
Cedrela odorata L. Analgesic
Cedrela odorata L. Antimalarial
Cedrela odorata L. Astringent
Cedrela odorata L. Collyrium
Cedrela odorata L. Emetic
Cedrela odorata L. Febrifuge
Cedrela odorata L. Hypotensive
Cedrela odorata L. Insectifuge
Cedrela odorata L. Molluscacide
Cedrela odorata L. Orexigenic
Cedrela odorata L. Pectoral
Cedrela odorata L. Tonic
Cedrela odorata L. Vasodilator
Cedrela odorata L. Vermifuge

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00039764 External link 512 Mexicanolide
CHEMBL1080142
CHEMBL1398245
CHEMBL1979074
3 / 2 / 4 No. 102
C00049417 External link 512 6-Deoxy-9alpha-hydroxycedrodorin
No. 255
C00033713 External link 512 Cedrodorin
No. 255
C00049416 External link 512 6-Acetoxycedrodorin
No. 255
C00049419 External link 512 9alpha-Hydroxycedrodorin
No. 255
C00032088 External link 512 Odoratone
CHEMBL1395387
5 / 11 / 40 No. 264 No. 51
C00000988 External link 512 Odoratol
No. 1331 No. 13

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00032088 C00039764 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00032088 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00039764 2 / 3
P04637 Cellular tumor antigen p53 Transcription Factor C00032088 7 / 37
P28482 Mitogen-activated protein kinase 1 Erk C00032088 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00039764 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00032088 4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (43)

KEGG name UniProt
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)