| Organism name | Sideritis spp. |
|---|---|
| Genus | Sideritis |
| Family | Labiatae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Sideritis |
|---|---|
| Linked NCBI taxonomy ID | 155231 |
| Linked level | genus |
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00013641
|
8-Hydroxyapigenin 7-glucosyl-(1->2)-xyloside
/ 7-[(2-O-beta-D-Glucopyranosyl-beta-D-xylopyranosyl)oxy]-5,8-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
No. 1 | No. 15 |
|
||||
|
C00003891
|
Demethoxycentaureidin
/ Desmethoxycentaureidin / 5,7,3'-Trihydroxy-6,4'-dimethoxyflavone / 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one |
CHEMBL74838
|
No. 3 | No. 15 |
|
|||
|
C00001016
|
7-O-Methylacacetin
/ Acacetin 7-methyl ether / Genkwanin 4'-methyl ether / Apigenin 7,4'-dimethyl ether / 5-Hydroxy-4',7-dimethoxyflavone / 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL350958
|
C044998
|
1 / 0 / 0 | No. 3 | No. 15 |
|
|
|
C00003865
|
7-O-Methylluteolin
/ Luteolin 7-methyl ether / 5,3',4'-Trihydroxy-7-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL183745
|
C051414
|
1 / 1 / 2 | No. 3 | No. 15 |
|
|
|
C00013595
|
Eupatrin
/ Anisomelin / Fastigenin / Cirsilineol / 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone |
CHEMBL487213
|
C057618
|
No. 3 | No. 15 |
|
||
|
C00003894
|
Eupatorin
/ 3',5-Dihydroxy-4',6,7-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL487402
|
C103110
|
5 / 5 / 4 | 5 / 0 | No. 3 | No. 15 |
|
|
C00003870
|
Luteolin 7,3',4'-trimethyl ether
/ 5-Hydroxy-7,3',4'-trimethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL468876
|
No. 35 | No. 15 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P00747 | Plasminogen | S1A | C00003865 | 1 / 2 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001016 | 0 / 0 |
| O14965 | Aurora kinase A | Aur | C00003894 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00003894 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00003894 | 4 / 4 |
| Q96GD4 | Aurora kinase B | Aur | C00003894 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00003894 | 1 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003894
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00003894
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003894
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00003894
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003894
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #604229 | Peters anomaly |
Q16678
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00747
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|