| Organism name | Helichrysum nitens | 
|---|---|
| Genus | Helichrysum | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Helichrysum | 
|---|---|
| Linked NCBI taxonomy ID | 59430 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00003831   | Alnetin | No. 3 | No. 15 |   | ||||
| C00004550   | 3,5,6,7-Tetramethoxyflavone / 3,5,6,7-Tetramethoxy-2-phenyl-4H-1-benzopyran-4-one | No. 3 | No. 15 |   | ||||
| C00003832   | 5,6,7,8-Tetramethoxyflavone / 5,6,7,8-Tetramethoxy-2-phenyl-4H-1-benzopyran-4-one | No. 3 | No. 15 |   | ||||
| C00004590   | 3,5,6,7,8-Pentamethoxyflavone | No. 8 | No. 15 |   | ||||
| C00003808   | Baicalein 5,6,7-trimethyl ether | CHEMBL182992 | No. 35 | No. 15 |   | |||
| C00001042   | 3,5,7-trimethoxyflavone / Galangin trimethyl ether / Galangin 3,5,7-trimethyl ether | CHEMBL75772 | 1 / 0 / 0 | No. 35 | No. 15 |   | ||
| C00001028   | 5,7-Dimethoxyflavone / chrysin 5,7-dimethyl ether | CHEMBL275391 | C060298 | 14 / 13 / 13 | 2 / 3 | No. 35 | No. 15 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001042 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001028 | 0 / 0 | 
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001028 | 0 / 0 | 
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00001028 | 4 / 2 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001028 | 0 / 0 | 
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00001028 | 2 / 2 | 
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001028 | 2 / 0 | 
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001028 | 1 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001028 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001028 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001028 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001028 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00001028 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001028 | 1 / 2 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001028 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00001028 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00001028 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 | P51843 | 
| #300200 | Adrenal hypoplasia, congenital; ahc | P51843 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #614490 | Blood group, junior system; jr | Q9UNQ0 | 
| #114480 | Breast cancer | P38398 | 
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 | P38398 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #257220 | Niemann-pick disease, type c1; npc1 | O15118 | 
| #167000 | Ovarian cancer | P38398 | 
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 | P38398 | 
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | Q9UNQ0 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00136 | Niemann-Pick disease type C (NPC) | O15118
                            (related) | 
| H00027 | Ovarian cancer | P38398
                            (related) | 
| H00031 | Breast cancer | P38398
                            (related) | 
| H00552 | Glycerol kinase deficiency (GKD) | P51843
                            (related) | 
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) | P51843
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | Q13148
                            (related) |