Organism name | Plectranthus fruticosus |
---|---|
Genus | Plectranthus |
Family | Labiatae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Plectranthus fruticosus |
---|---|
Linked NCBI taxonomy ID | 306376 |
Linked level | species |
Family in NCBI taxonomy | Lamiaceae |
---|---|
ID | 4136 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00001043
![]() |
Genkwanin
|
CHEMBL210635
|
C014568
|
5 / 4 / 5 | 3 / 0 | No. 3 | No. 15 |
![]() |
C00003837
![]() |
Cirsimaritin
|
CHEMBL348436
|
C007072
|
13 / 18 / 14 | No. 3 | No. 15 |
![]() |
|
C00003894
![]() |
Eupatorin
/ 3',5-Dihydroxy-4',6,7-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL487402
|
C103110
|
5 / 5 / 4 | 5 / 0 | No. 3 | No. 15 |
![]() |
C00003840
![]() |
Salvigenin
|
CHEMBL376644
|
C014049
|
No. 35 | No. 15 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001043 C00003894 | 0 / 0 |
Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001043 C00003894 | 4 / 4 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00003837 | 7 / 3 |
P06746 | DNA polymerase beta | Enzyme | C00003837 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00003837 | 6 / 4 |
O14965 | Aurora kinase A | Aur | C00003894 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00003837 | 0 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00003837 | 0 / 0 |
Q9Y3R4 | Sialidase-2 | Enzyme | C00001043 | 0 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003837 | 0 / 0 |
P33765 | Adenosine receptor A3 | Adenosine receptor | C00003837 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00003837 | 1 / 1 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003837 | 0 / 3 |
P04745 | Alpha-amylase 1 | Enzyme | C00001043 | 0 / 0 |
Q96GD4 | Aurora kinase B | Aur | C00003894 | 0 / 0 |
P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00003894 | 1 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003837 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00003837 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00003837 | 4 / 3 |
P06239 | Tyrosine-protein kinase Lck | Src | C00001043 | 0 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00003837 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001043
C00003894
|
1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001043
C00003894
|
1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003894
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001043
|
1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00003894
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003894
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
#231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
#137760 | Glaucoma, primary open angle; poag |
Q16678
|
#602089 | Hemangioma, capillary infantile |
P35968
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#604229 | Peters anomaly |
Q16678
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00017 | Esophageal cancer |
P35354
(related)
|
H00025 | Penile cancer |
P35354
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00612 | Primary open angle glaucoma |
Q16678
(related)
|
H01075 | Peters anomaly |
Q16678
(related)
|
H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|