Species

KNApSAcK Entry

Organism name Viola yedoensis
Genus Viola
Family Violaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Viola philippica
Linked NCBI taxonomy ID 316493
Linked level species

Family

Family in NCBI taxonomy Violaceae
ID 24921

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00014029 External link 512 6-C-alpha-L-Arabinopyranosyl-8-C-beta-L-arabinopyranosylapigenin
No. 1 No. 15
C00006166 External link 512 6-C-beta-D-Xylopyranosyl-8-C-alpha-L-arabinopyranosylapigenin
No. 1 No. 15
C00006177 External link 512 Shaftoside
/ Schaftoside
CHEMBL1537012
7 / 2 / 2 No. 1 No. 15
C00006187 External link 512 Isocarlinoside
No. 1 No. 15
C00006382 External link 512 Neoschaftoside
CHEMBL1537012
7 / 2 / 2 No. 1 No. 15
C00006381 External link 512 Isoshaftoside
/ Isoschaftoside
/ Apigenin 6-C-alpha-L-arabinopyranoside-8-C-beta-D-glucopyranoside
No. 1 No. 15
C00006229 External link 512 Vicenin 2
/ Apigenin 6,8-di-C-glucoside
CHEMBL1442950
6 / 14 / 8 No. 1 No. 15
C00001055 External link 512 Isoorientin
/ Homoorientin
/ Lespecapitioside
/ Luteolin 6-C-beta-D-glucopyranoside
/ 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
CHEMBL239559
CHEMBL1302308
C057912
23 / 14 / 17 0 / 1 No. 22 No. 15

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001055 C00006177 C00006229 C00006382 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001055 C00006177 C00006229 C00006382 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001055 C00006177 C00006382 0 / 0
P06746 DNA polymerase beta Enzyme C00001055 C00006177 C00006382 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001055 C00006177 C00006382 1 / 1
P39748 Flap endonuclease 1 Enzyme C00001055 C00006177 C00006382 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001055 C00006177 C00006382 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001055 C00006229 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001055 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001055 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001055 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001055 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001055 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00006229 7 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00001055 4 / 3
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001055 0 / 0
P04062 Glucosylceramidase Enzyme C00006229 6 / 4
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00006229 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001055 1 / 1
O00255 Menin Unclassified protein C00001055 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001055 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00001055 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001055 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001055 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00001055 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001055 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (24)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008104 Liver Cirrhosis, Alcoholic C00001055