Species

KNApSAcK Entry

Organism name Stachys scardica Griseb.
Genus Stachys
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stachys
Linked NCBI taxonomy ID 53171
Linked level genus

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004458 External link 512 Selgin 7-O-glucoside
No. 2 No. 15
C00004444 External link 512 Tricin 7-glucoside
/ Tricin 7-O-glucoside
/ Tricin 7-O-beta-D-glucopyranoside
No. 2 No. 15
C00004418 External link 512 Hypolaetin 7-O-glucoside
No. 2 No. 15
C00001055 External link 512 Isoorientin
/ Homoorientin
/ Lespecapitioside
/ Luteolin 6-C-beta-D-glucopyranoside
/ 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
CHEMBL239559
CHEMBL1302308
C057912
23 / 14 / 17 0 / 1 No. 22 No. 15
C00001110 External link 512 Vitexin
/ Apigenin 8-C-glucoside
/ 8-D-Glucosyl-4',5,7-trihydroxyflavone
/ 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL487417
CHEMBL1332209
CHEMBL1357921
16 / 4 / 8 No. 22 No. 15
C00004172 External link 512 Echinacin
/ (-)-Echinacin
/ Apigenin 7-O-p-coumaroylglucoside
/ Apigenin 7-(6''-p-coumarylglucoside)
/ Apigenin 7-O-(6''-O-p-coumaroylglucoside)
C084441
No. 30 No. 15

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001055 C00001110 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001055 C00001110 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00001055 C00001110 1 / 4
Q13951 Core-binding factor subunit beta Unclassified protein C00001055 C00001110 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001055 C00001110 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001055 C00001110 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001055 C00001110 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001055 C00001110 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001055 C00001110 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001110 0 / 1
O75496 Geminin Unclassified protein C00001110 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001055 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001110 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001055 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001110 1 / 1
P15121 Aldose reductase Enzyme C00001110 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001055 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001055 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001110 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00001055 4 / 3
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001110 1 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001055 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001055 1 / 1
O00255 Menin Unclassified protein C00001055 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001055 1 / 2
P10253 Lysosomal alpha-glucosidase Hydrolase C00001055 1 / 1
P06746 DNA polymerase beta Enzyme C00001055 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001055 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00001055 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001055 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (20)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008104 Liver Cirrhosis, Alcoholic C00001055