| Organism name | Prosopis kuntzei | 
|---|---|
| Genus | Prosopis | 
| Family | Fabaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Prosopis kuntzei | 
|---|---|
| Linked NCBI taxonomy ID | 207715 | 
| Linked level | species | 
| Family in NCBI taxonomy | Fabaceae | 
|---|---|
| ID | 3803 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | 
                        # of proteins in
                         ChEMBL interaction / related OMIM / related KEGG DISEASE  | 
                      
                        # of genes in
                         CTD interaction / related diseases  | 
                      
                        KCF-S
                         cluster  | 
                      
                        phytochemical
                         cluster  | 
                      figure | 
|---|---|---|---|---|---|---|---|---|
| 
                        C00001059
                        
                           | 
                      
                        Isovitexin
                         / Saponaretin / Homovitexin / 6-C-beta-D-Glucopyranosylapigenin / 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone / 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one  | 
                      
                        CHEMBL465360
                         CHEMBL1601394  | 
                      
                        C049772
                         | 
                      28 / 20 / 19 | No. 22 | No. 15 | 
                         
                       | 
                    |
| 
                        C00001110
                        
                           | 
                      
                        Vitexin
                         / Apigenin 8-C-glucoside / 8-D-Glucosyl-4',5,7-trihydroxyflavone / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one  | 
                      
                        CHEMBL487417
                         CHEMBL1332209 CHEMBL1357921  | 
                      16 / 4 / 8 | No. 22 | No. 15 | 
                         
                       | 
                    ||
| 
                        C00002519
                        
                           | 
                      
                        Dalbergin
                         / 6-Hydroxy-7-methoxy-4-phenylcoumarin  | 
                      
                        CHEMBL1829658
                         | 
                      No. 54 | No. 17 | 
                         
                       | 
                    
| accession | description | class description | KNApSAcK metabolite in interactions | 
                          # of diseases
                           (OMIM / KEGG)  | 
                      
|---|---|---|---|---|
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001059 C00001110 | 0 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001059 C00001110 | 0 / 0 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001059 C00001110 | 1 / 4 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001059 C00001110 | 0 / 1 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001059 C00001110 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001059 C00001110 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001059 C00001110 | 0 / 0 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001059 C00001110 | 0 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00001059 C00001110 | 1 / 1 | 
| P30989 | Neurotensin receptor type 1 | Neurotensin receptor | C00001059 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00001110 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00001110 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001059 | 7 / 3 | 
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001059 | 2 / 2 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001059 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001110 | 0 / 0 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001059 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00001059 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001110 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001110 | 0 / 1 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001059 | 1 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001059 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001110 | 0 / 1 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001059 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001110 | 1 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001059 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001059 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001059 | 1 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001059 | 1 / 0 | 
| O00255 | Menin | Unclassified protein | C00001059 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001059 | 1 / 2 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001059 | 1 / 1 | 
| P06746 | DNA polymerase beta | Enzyme | C00001059 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001059 | 0 / 0 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001059 | 2 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | 
                            P63092
                             | 
                        
| #114500 | Colorectal cancer; crc | 
                            Q14191
                             | 
                        
| #609535 | Drug metabolism, poor, cyp2c19-related | 
                            P33261
                             | 
                        
| #608902 | Drug metabolism, poor, cyp2d6-related | 
                            P10635
                             | 
                        
| #137800 | Glioma susceptibility 1; glm1 | 
                            O75874
                             | 
                        
| #232300 | Glycogen storage disease ii | 
                            P10253
                             | 
                        
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | 
                            Q03164
                             | 
                        
| #145000 | Hyperparathyroidism 1; hrpt1 | 
                            O00255
                             | 
                        
| #174800 | Mccune-albright syndrome; mas | 
                            P63092
                             | 
                        
| #131100 | Multiple endocrine neoplasia, type i; men1 | 
                            O00255
                             | 
                        
| #160900 | Myotonic dystrophy 1; dm1 | 
                            Q9NR56
                             | 
                        
| #257200 | Niemann-pick disease, type a | 
                            P17405
                             | 
                        
| #607616 | Niemann-pick disease, type b | 
                            P17405
                             | 
                        
| #166350 | Osseous heteroplasia, progressive; poh | 
                            P63092
                             | 
                        
| #102200 | Pituitary adenoma, growth hormone-secreting | 
                            P63092
                             | 
                        
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | 
                            Q01196
                             | 
                        
| #103580 | Pseudohypoparathyroidism, type ia; php1a | 
                            P63092
                             | 
                        
| #603233 | Pseudohypoparathyroidism, type ib; php1b | 
                            P63092
                             | 
                        
| #612462 | Pseudohypoparathyroidism, type ic; php1c | 
                            P63092
                             | 
                        
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | 
                            Q9NUW8
                             | 
                        
| #277700 | Werner syndrome; wrn | 
                            Q14191
                             | 
                        
| #278750 | Xeroderma pigmentosum, variant type; xpv | 
                            Q9Y253
                             | 
                        
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | 
                            O00255
                            (related)
                             | 
                        
| H00034 | Carcinoid | 
                            O00255
                            (related)
                             | 
                        
| H00045 | Malignant islet cell carcinoma | 
                            O00255
                            (related)
                             | 
                        
| H00246 | Primary hyperparathyroidism | 
                            O00255
                            (related)
                             | 
                        
| H01102 | Pituitary adenomas | 
                            O00255
                            (related)
                             | 
                        
| H00036 | Osteosarcoma | 
                            P08684
                            (marker)
                             | 
                        
| H00069 | Glycogen storage diseases (GSD) | 
                            P10253
                            (related)
                             | 
                        
| H01205 | Coumarin resistance | 
                            P11712
                            (related)
                             | 
                        
| H00137 | Niemann-Pick disease (NPD) typeA and B | 
                            P17405
                            (related)
                             | 
                        
| H00424 | Defects in the degradation of sphingomyelin | 
                            P17405
                            (related)
                             | 
                        
| H01171 | Poor drug metabolism (PM) | 
                            P33261
                            (related)
                             | 
                        
| H00244 | Pseudohypoparathyroidism | 
                            P63092
                            (related)
                             | 
                        
| H00441 | Progressive osseous heteroplasia (POH) | 
                            P63092
                            (related)
                             | 
                        
| H00501 | Fibrous dysplasia, polyostotic | 
                            P63092
                            (related)
                             | 
                        
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | 
                            Q01196
                            (related)
                             Q01196 (marker) Q03164 (related) Q03164 (marker)  | 
                        
| H00003 | Acute myeloid leukemia (AML) | 
                            Q01196
                            (related)
                             Q01196 (marker) Q13951 (marker)  | 
                        
| H00004 | Chronic myeloid leukemia (CML) | 
                            Q01196
                            (related)
                             | 
                        
| H00978 | Thrombocytopenia (THC) | 
                            Q01196
                            (related)
                             | 
                        
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | 
                            Q03164
                            (related)
                             | 
                        
| H00296 | Defects in RecQ helicases | 
                            Q14191
                            (related)
                             | 
                        
| H00063 | Spinocerebellar ataxia (SCA) | 
                            Q9NUW8
                            (related)
                             | 
                        
| H00403 | Disorders of nucleotide excision repair | 
                            Q9Y253
                            (related)
                             |